7-Xylosyl-10-deacetylbaccatin III | CAS:157664-03-4

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Enzymic hydrolysis of 7-xylosyltaxanes by xylosidase from Moraxella sp.[Reference: WebLink]

The production of large quantities of paclitaxel for use as an anticancer treatment has been a difficult problem because of the low concentration of the compound in yew trees (Taxus sp.) and its occurrence as part of a mixture of other taxanes. 7-Xylosyltaxanes are major components of the mixture found in the bark of the Pacific yew (Taxus brevifolia).
METHODS AND RESULTS:
A bacterial strain isolated from soil and identified as a Moraxella sp. was able to remove the xylosyl group from 7-xylosylpaclitaxel 7-xylosyl-10-deacetylpaclitaxel, 7-xylosylbaccatin III and 7-Xylosyl-10-deacetylbaccatin III, thereby making the xylosyltaxanes available as sources of 10-deacetylbaccatin III for semisynthesis of paclitaxel.
CONCLUSIONS:
The activity was located in both the soluble and particulate fractions of the cell.

Product Name	7-Xylosyl-10-deacetylbaccatin III
CAS No.:	157664-03-4
Catalog No.:	CFN89390
Molecular Formula:	C₃₄H₄₄O₁₄
Molecular Weight:	676.70 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The barks of Taxus brevifolia.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Price: