7-O-Methyleriodictyol | CAS:51857-11-5

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Isolation and biological effects of 7-O-methyleriodictyol, a flavanone isolated from Artemisia monosperma, on rat isolated smooth muscles.[Pubmed: 8441781]

METHODS AND RESULTS:
The isolation for the first time from the genus Artemisia (Compositae) of the known flavanone, 7-O-Methyleriodictyol (7-methoxy-5,3',4'-trihydroxy-flavanone), its identification, and its biological effects on rat isolated smooth muscles are described. 7-O-Methyleriodictyol (10(-7) M to 3 x 10(-4) M) caused concentration-dependent inhibition of the amplitude of the phasic contractions and reduced the tone of the ileum, the uterus, and the urinary bladder. It also caused relaxation of the phenylephrine-precontracted pulmonary artery and the acetylcholine-precontracted trachea. The flavanone also shifted to the right the acetylcholine concentration-effect curve on the ileum and the oxytocin concentration-effect curve on the uterus. The maximum contractions induced by acetylcholine or oxytocin were also inhibited by 7-O-Methyleriodictyol.
CONCLUSIONS:
These antispasmodic effects are partly consistent with the use of A. monosperma in folk medicine for certain gastrointestinal disorders.

Product Name	7-O-Methyleriodictyol
CAS No.:	51857-11-5
Catalog No.:	CFN98833
Molecular Formula:	C₁₆H₁₄O₆
Molecular Weight:	302.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Targets:	AChR
Source:	The branches of Viscum coloratum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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