4-Hydroxybenzamide

4-Hydroxybenzamide
Product Name 4-Hydroxybenzamide
CAS No.: 619-57-8
Catalog No.: CFN97063
Molecular Formula: C7H7NO2
Molecular Weight: 137.1 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Berberis pruinosa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $30/20mg
4-Hydroxybenzamide is a natural product from Berberis pruinosa.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Pharmaceuticals (Basel).2021, 14(8):742.
  • Preprints2021, doi:10.20944
  • Int J Mol Sci.2022, 23(1):538.
  • Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2020, 37(9):1437-1448.
  • Microchemical Journal2022, 182: 107874.
  • Foods.2022, 12(1):136.
  • Molecules.2021, 26(12):3652.
  • Plant Physiol Biochem.2021, 160:166-174.
  • Aging (Albany NY).2023, 15(24):15557-15577.
  • Molecules.2021, 26(18):5665.
  • Hydroxytyrosol 1-O-glucoside

    Catalog No: CFN95367
    CAS No: 76873-99-9
    Price: $318/10mg
    Cuneataside C

    Catalog No: CFN95368
    CAS No: 871720-16-0
    Price: $318/10mg
    New compound 43

    Catalog No: CFN95899
    CAS No: N/A
    Price: $318/5mg
    Cistanoside F

    Catalog No: CFN93304
    CAS No: 97411-47-7
    Price: Inquiry(manager@chemfaces.com)
    4-Methoxy hydroxytyrosol 1-O-glucoside

    Catalog No: CFN95775
    CAS No: N/A
    Price: $318/10mg
    Hydroxytyrosol acetate

    Catalog No: CFN90927
    CAS No: 69039-02-7
    Price: $80/20mg
    p-Hydroxyphenethyl anisate

    Catalog No: CFN96586
    CAS No: 87932-34-1
    Price: $60/20mg
    p-Hydroxyphenethyl vanillate

    Catalog No: CFN89272
    CAS No: 1539303-03-1
    Price: Inquiry(manager@chemfaces.com)
    4'-Hydroxyacetophenone

    Catalog No: CFN97575
    CAS No: 99-93-4
    Price: $30/20mg
    4-Hydroxybenzamide

    Catalog No: CFN97063
    CAS No: 619-57-8
    Price: $30/20mg
    J Phys Chem B. 2015 Aug 20;119(33):10466-77.
    Influence of Secondary Interactions on the Structure, Sublimation Thermodynamics, and Solubility of Salicylate:4-Hydroxybenzamide Cocrystals. Combined Experimental and Theoretical Study.[Pubmed: 26258951]
    Cocrystal screening of 4-Hydroxybenzamide with a number of salicylates (salicylic acid, SA; 4-aminosalicylic acid, PASA; acetylsalicylic acid, ASA; and salicylsalicylic acid, SSA) was conducted to confirm the formation of two cocrystals, [SA+4-OHBZA] (1:1) and [PASA+4-OHBZA] (1:1).
    METHODS AND RESULTS:
    Their structures were determined using single-crystal X-ray diffraction, and the hydrogen-bond network topology was studied. Thermodynamic characteristics of salicylic acid cocrystal sublimation were obtained experimentally. It was proved that PASA cocrystallization with 4-OHBZA makes the drug more stable and prevents the irreversible process of decarboxylation of PASA resulting in formation of toxic 3-aminophenol. The pattern of non-covalent interactions in the cocrystals is described quantitatively using solid-state density functional theory followed by Bader analysis of the periodic electron density. It has been found that the total energy of secondary interactions between synthon atoms and the side hydroxyl group of the acid molecule in [SA+4-OHBZA] (1:1) and [PASA+4-OHBZA] (1:1) cocrystals is comparable to the energy of the primary acid-amide heterosynthon. The theoretical value of the sublimation enthalpy of [SA+4-OHBZA], 231 kJ/mol, agrees fairly well with the experimental one, 272 kJ/mol.
    CONCLUSIONS:
    The dissolution experiments with [SA+4-OHBZA] have proved that the relatively large cocrystal stability in relation to the stability of its components has a negative effect on the dissolution rate and equilibrium solubility. The [PASA+4-OHBZA] (1:1) cocrystal showed an enhancement of apparent solubility compared to that of the corresponding pure active pharmaceutical ingredient, while their intrinsic dissolution rates are comparable.
    Epimedin K

    Catalog No: CFN95019
    CAS No: 174286-13-6
    Price: $288/5mg
    Polygalasaponin XLIX

    Catalog No: CFN95117
    CAS No: 1033593-12-2
    Price: $318/10mg
    Pterodonoic acid

    Catalog No: CFN95183
    CAS No: 62458-42-8
    Price: $413/5mg
    Vanillic acid glucoside

    Catalog No: CFN95257
    CAS No: 32142-31-7
    Price: $368/10mg
    11-Deoxyisomogroside V

    Catalog No: CFN95288
    CAS No: 1628293-32-2
    Price: $368/10mg
    Eriodictyol 7-O-glucuronide

    Catalog No: CFN95290
    CAS No: 125535-06-0
    Price: $318/10mg
    New compound 8

    Catalog No: CFN95341
    CAS No: N/A
    Price: $318/5mg
    Violanone

    Catalog No: CFN95385
    CAS No: 52250-38-1
    Price: $318/10mg
    6-Methoxyfraxinellone

    Catalog No: CFN95485
    CAS No: N/A
    Price: $318/10mg
    11alpha-hydroxy-3,7-dioxo-5alpha-lanosta-8,24(E)-dien-26-oic acid

    Catalog No: CFN95592
    CAS No: 1245703-70-1
    Price: $413/5mg