3-O-Caffeoylquinic acid methyl ester

3-O-Caffeoylquinic acid methyl ester
Product Name 3-O-Caffeoylquinic acid methyl ester
CAS No.: 123483-19-2
Catalog No.: CFN92573
Molecular Formula: C17H20O9
Molecular Weight: 368.3 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The fruits of Morus alba L
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $268/20mg
3-O-Caffeoylquinic acid methyl ester is a natural product from Morus alba L.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Heinrich Heine University Dusseldorf2021, 62203.
  • Biomed Chromatogr.2019, 8:e4774
  • Indian J. of Experimental Bio.2020, 9(58).
  • Food Sci Nutr.2023, 11(9):5532-5542.
  • J Nat Prod.2023, 86(2):264-275.
  • Int J Mol Sci.2018, 19(2)
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • Biotechnol Bioeng.2020, 117(7):2198-2208.
  • Nat Prod Commun.2014, 9(5):679-82
  • Sci Rep.2017, 7:40345
  • Ethyl chlorogenate

    Catalog No: CFN91565
    CAS No: 425408-42-0
    Price: Inquiry(manager@chemfaces.com)
    New compound 46

    Catalog No: CFN95921
    CAS No: N/A
    Price: $318/5mg
    3-O-Feruloylquinic acid

    Catalog No: CFN92393
    CAS No: 1899-29-2
    Price: Inquiry(manager@chemfaces.com)
    cis-3-O-Feruloylquinic acid

    Catalog No: CFN95731
    CAS No: 89886-27-1
    Price: $318/5mg
    Methyl 3-O-feruloylquinate

    Catalog No: CFN92446
    CAS No: 154418-15-2
    Price: $318/5mg
    Cyclohexanecarboxylic acid

    Catalog No: CFN92529
    CAS No: 327161-03-5
    Price: Inquiry(manager@chemfaces.com)
    4-O-Coumaroylquinic acid

    Catalog No: CFN95508
    CAS No: 53539-37-0
    Price: $318/5mg
    Cryptochlorogenic acid

    Catalog No: CFN99117
    CAS No: 905-99-7
    Price: $90/20mg
    Methyl 4-caffeoylquinate

    Catalog No: CFN92528
    CAS No: 123372-74-7
    Price: Inquiry(manager@chemfaces.com)
    4-O-Feruloylquinic acid

    Catalog No: CFN92392
    CAS No: 2613-86-7
    Price: $368/10mg
    Planta Med. 2004 Aug;70(8):711-7.
    Inhibiting activities of the secondary metabolites of Phlomis brunneogaleata against parasitic protozoa and plasmodial enoyl-ACP Reductase, a crucial enzyme in fatty acid biosynthesis.[Pubmed: 15326547 ]
    Anti-plasmodial activity-guided fractionation of Phlomis brunneogaleata (Lamiaceae) led to the isolation of two new metabolites, the iridoid glycoside, brunneogaleatoside and a new pyrrolidinium derivative (2 S,4 R)-2-carboxy-4-( E)- p-coumaroyloxy-1,1-dimethylpyrrolidinium inner salt [(2 S,4 R)-1,1-dimethyl-4-( E)- p-coumaroyloxyproline inner salt]. Moreover, a known iridoid glycoside, ipolamiide, six known phenylethanoid glycosides, verbascoside, isoverbascoside, forsythoside B, echinacoside, glucopyranosyl-(1-->G (i)-6)-martynoside and integrifolioside B, two flavone glycosides, luteolin 7- O-beta- D-glucopyranoside ( 10) and chrysoeriol 7- O-beta- D-glucopyranoside ( 11), a lignan glycoside liriodendrin, an acetophenone glycoside 4-hydroxyacetophenone 4- O-(6'- O-beta- D-apiofuranosyl)-beta- D-glucopyranoside and three caffeic acid esters, chlorogenic acid, 3-O-Caffeoylquinic acid methyl ester and 5- O-caffeoylshikimic acid were isolated.
    METHODS AND RESULTS:
    The structures of the pure compounds were elucidated by means of spectroscopic methods (UV, IR, MS, 1D and 2D NMR, [alpha] (D)) and X-ray crystallography. Compounds 10 and 11 were determined to be the major anti-malarial principles of the crude extract (IC (50) values of 2.4 and 5.9 micrograms/mL, respectively). They also exhibited significant leishmanicidal activity (IC (50) = 1.1 and 4.1 micrograms/mL, respectively). The inhibitory potential of the pure metabolites against plasmodial enoyl-ACP reductase (FabI), which is the key regulator of type II fatty acid synthases (FAS-II) in P. falciparum, was also assessed.
    CONCLUSIONS:
    Compound 10 showed promising FabI inhibiting effect (IC (50) = 10 micrograms/mL) and appears to be the first anti-malarial natural product targeting FabI of P. falciparum.
    Yao Xue Xue Bao. 2014 Apr;49(4):504-6.
    Studies on chemical constituents from fruits of Morus alba L.[Pubmed: 24974468]
    Chemical investigation of fruits of Mours alba L. lead to the isolation of fifteen compounds by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography.
    METHODS AND RESULTS:
    Their structures were determined to be: 1-[5-(2-formlfuryl) methyl] dihydrogen 2-hydroxypropane-1, 2, 3-tricarboxylate 2, 3-diethyl ester (1), 1-[2-(furan-2-yl)-2-oxoethyl] pyrrolidin-2-one (2), divaricataester A (3), methyl 1-[2-(furan-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carboxylate (4), 1-[2-(furan-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carboxylic acid (5), L-pyroglutamic acid (6), L-pyroglutamic acid ethyl ester (7), 3-O-Caffeoylquinic acid methyl ester (8), 3-O-caffeoylquinic acid ethyl ester (9), 5-O-caffeoylquinic acid methyl ester (10), 5-O-caffeoylquinic acid ethyl ester (11), 4-O-caffeoylquinic acid methyl ester (12), 4-O-caffeoylquinic acid methyl ester (13), 4-O-caffeoylquinic acid (14), 3-O-caffeoylquinic acid (15), respectively, based on the spectral analysis such as NMR, MS etc.
    CONCLUSIONS:
    Compounds 1-14 were isolated from this genus for the first time, among which 1 was a new compound.
    1-O-galloyl-6-O-cinnamoylglucose

    Catalog No: CFN95053
    CAS No: 115746-69-5
    Price: $338/5mg
    Tangshenoside I

    Catalog No: CFN95108
    CAS No: 117278-74-7
    Price: $338/10mg
    Polygalin C

    Catalog No: CFN95118
    CAS No: 934768-05-5
    Price: $288/5mg
    Yuankanin

    Catalog No: CFN95128
    CAS No: 77099-20-8
    Price: $318/5mg
    Formononetin-8-C-beta-D-apiofuranosyl-(1->6)-O-beta-D-glucopyranoside

    Catalog No: CFN95157
    CAS No: 1147858-78-3
    Price: $318/10mg
    Licoflavanone

    Catalog No: CFN95213
    CAS No: 119240-82-3
    Price: $413/5mg
    Solafuranone

    Catalog No: CFN95312
    CAS No: 367965-50-2
    Price: $318/5mg
    Yakuchinone A

    Catalog No: CFN95555
    CAS No: 78954-23-1
    Price: $318/10mg
    Methyl ganoderate E

    Catalog No: CFN95582
    CAS No: 98718-43-5
    Price: $413/5mg
    N-Methyltetrahydrocolumbamine

    Catalog No: CFN95590
    CAS No: 92758-34-4
    Price: $318/10mg