2-Hydroxynaringenin

2-Hydroxynaringenin
Product Name 2-Hydroxynaringenin
CAS No.: 58124-18-8
Catalog No.: CFN97950
Molecular Formula: C15H12O6
Molecular Weight: 288.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Flemingia macrophylla
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
The recombinant protein exhibits high FNS I activity catalyzing the conversion of naringenin to apigenin and 2-Hydroxynaringenin.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • US20170000760 A12016, 42740
  • ACS Synth Biol.2022, 11(10):3296-3304.
  • Food Funct.2023, 14(9):4354-4367.
  • J Pharm Biomed Anal.2017, 140:274-280
  • Korean J Acupunct2020, 37:104-121
  • ScientificWorldJournal.2022, 2022:4806889.
  • Molecules.2019, 24(4):E709
  • Neurochem Int.2020, 133:104629
  • Allergol Immunopathol (Madr).2022, 1;50(4):23-30.
  • Drug Chem Toxicol.2020, 1-12.
  • Garbanzol

    Catalog No: CFN96497
    CAS No: 1226-22-8
    Price: Inquiry(manager@chemfaces.com)
    Aromadendrin

    Catalog No: CFN98736
    CAS No: 480-20-6
    Price: $318/20mg
    3-Hydroxy-4',5,7-trimethoxyflavanone

    Catalog No: CFN97247
    CAS No: 76792-94-4
    Price: Inquiry(manager@chemfaces.com)
    6-Methyl-7-O-methylaromadendrin

    Catalog No: CFN96109
    CAS No: 852385-13-8
    Price: Inquiry(manager@chemfaces.com)
    Gericudranin E

    Catalog No: CFN91902
    CAS No: 172104-07-3
    Price: Inquiry(manager@chemfaces.com)
    2-Hydroxynaringenin

    Catalog No: CFN97950
    CAS No: 58124-18-8
    Price: Inquiry(manager@chemfaces.com)
    FEBS Lett. 2014 Jun 27;588(14):2307-14.
    Functional characterization of a Plagiochasma appendiculatum flavone synthase I showing flavanone 2-hydroxylase activity.[Pubmed: 24859082]
    FNS I is a 2-oxoglutarate dependent dioxygenase (2-ODD) found mainly in species of the Apiaceae family.
    METHODS AND RESULTS:
    Here, an FNS I cDNA sequence was isolated from the liverwort Plagiochasma appendiculatum (Aytoniaceae) and characterized. The recombinant protein exhibited high FNS I activity catalyzing the conversion of naringenin to apigenin and 2-Hydroxynaringenin. The critical residue for flavanone-2-hydroxylation activity was Tyr240, as identified from homology modeling and site-directed mutagenesis. The recombinant protein also showed some flavonol synthase activity, as it can convert dihydrokaempferol to kaempferol. When the Leu311 residue was mutated to Phe, the enzyme's capacity to convert dihydrokaempferol to kaempferol was substantially increased.
    CONCLUSIONS:
    PaFNS I represents a 2-ODD in which a hydrophobic π-stacking interaction between the key residue and the naringenin A-ring determines 2-hydroxyflavanone formation.
    7-Neohesperidosides

    Catalog No: CFN95018
    CAS No: 28383-41-7
    Price: $288/5mg
    Astin B

    Catalog No: CFN95188
    CAS No: 151201-76-2
    Price: $318/10mg
    Phyllanthusiin C

    Catalog No: CFN95260
    CAS No: 142674-52-0
    Price: $318/5mg
    15-Deoxypulic acid

    Catalog No: CFN95262
    CAS No: 95523-05-0
    Price: $368/5mg
    Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside

    Catalog No: CFN95277
    CAS No: 143016-74-4
    Price: $238/20mg
    3-O-Methylellagic acid 3'-O-alpha-rhamnopyranoside

    Catalog No: CFN95375
    CAS No: 352280-34-3
    Price: $413/5mg
    Lariciresinol 4-O-glucoside

    Catalog No: CFN95389
    CAS No: 143663-00-7
    Price: $318/5mg
    Barbaloin-related compound A

    Catalog No: CFN95453
    CAS No: 473225-21-7
    Price: $318/5mg
    Ganolucidic acid B

    Catalog No: CFN95513
    CAS No: 98683-75-1
    Price: $413/5mg
    Mahuannin G

    Catalog No: CFN95553
    CAS No: N/A
    Price: $318/5mg