14-Deoxycoleon U

14-Deoxycoleon U
Product Name 14-Deoxycoleon U
CAS No.: 88664-09-9
Catalog No.: CFN97924
Molecular Formula: C20H26O4
Molecular Weight: 330.4 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Yellow powder
Targets: Antifection
Source: The herbs of Coleus forskohlii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
14-Deoxycoleon U has anti-termitic activity, it is highly active against both wood-decay fungi. 14-Deoxycoleon U shows antibacterial activity against the Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Micrococcus luteus.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J AOAC Int.2021, 104(6):1634-1651.
  • Int J Mol Sci.2021, 22(16):8604.
  • Chinese J of Tissue Engineering Res.2022, 26(17): 2636-2641.
  • Molecules.2017, 22(6)
  • Microchemical Journal2022, 182: 107874.
  • Processes2021, 9(11),2065.
  • Toxicol In Vitro.2018, 52:94-105
  • J Food Biochem.2019, 43(9):e12970
  • Environ Toxicol.2021, 36(9):1848-1856.
  • Asian Journal of Chemistry2014, 26(22):7811-7816
  • Rosmaquinone

    Catalog No: CFN91824
    CAS No: 121927-71-7
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN96974
    CAS No: 113085-62-4
    Price: $318/10 mg

    Catalog No: CFN92990
    CAS No: 24703-38-6
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN91119
    CAS No: 111200-01-2
    Price: $368/10mg
    Carnosic acid

    Catalog No: CFN99102
    CAS No: 3650-09-7
    Price: $40/20mg
    12-O-Methylcarnosic acid

    Catalog No: CFN89377
    CAS No: 62201-71-2
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN92286
    CAS No: 16755-54-7
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN90366
    CAS No: 88664-08-8
    Price: $490/5mg

    Catalog No: CFN92243
    CAS No: 120278-22-0
    Price: Inquiry(manager@chemfaces.com)
    14-Deoxycoleon U

    Catalog No: CFN97924
    CAS No: 88664-09-9
    Price: Inquiry(manager@chemfaces.com)
    J Chem Ecol. 2010 Dec;36(12):1381-6.
    Antifungal abietane-type diterpenes from the cones of Taxodium distichum Rich.[Pubmed: 21072573]

    The chemical composition of Taxodium distichum cones and the antifungal activities of twelve diterpenoids against two wood decay fungi, Trametes versicolor (white-rot) and Fomitopsis palustris (brown-rot) were examined. The chemical composition of the major extractive fraction, the n-C(6)H(14) extract, was evaluated and its antifungal properties were identified. Twelve diterpenoids including ten abietane-type components were isolated from the n-C(6)H(14) extract: 6,7-dehydroferruginol (1), ferruginol (2), 6,7-dehydroroyleanone (3), sandaracopimaric acid (4), taxodione (5), taxodal (6), taxodone (7), sugiol (8), xanthoperol (9), salvinolone (10), 5,6-dehydrosugiol (11), and 14-Deoxycoleon U (12). Compounds 5 and 14-Deoxycoleon U were highly active against both wood-decay fungi. In particular, the activities of these compounds against F. palustris were potent.
    The results suggest that the position and the number of hydroxyl groups on abietane-type structures may be related to antifungal activities against T. versicolor and F. palustris.
    J Chem Ecol. 2009 Jun;35(6):635-42.
    Antitermitic activities of abietane-type diterpenes from Taxodium distichum cones.[Pubmed: 19475449 ]

    Eight known abietane-type diterpenes were isolated from the weak acidic fraction of the n-hexane extract from cones of Taxodium distichum, one of the extant, living fossil conifers. They were identified as 6,7-dehydroroyleanone (1), taxodal (2), taxodione (3), salvinolone (4), 14-Deoxycoleon U (5), 5,6-dehydrosugiol (6), sandaracopimaric acid (7), and xanthoperol (8). The structures of these compounds were determined by comparison of NMR spectral data with published data. The antitermitic (termicidal and antifeedant) activities of the compounds 1-8 against the subterranean termite, Reticulitermes speratus Kolbe, were evaluated.
    Compounds 1 and 3 showed potent termicidal activity, and 5 and 8 showed potent antifeedant activity. Compound 1 was found to be one of the representative bioactive compounds in the n-hexane extract of T. distichum cones. Compounds 1-8, with the exception of 7, were oxides of ferruginol (9). Therefore, the presence of various oxidation forms of the abietane-type structure reflects their various bioactivities.
    Bioorg Med Chem Lett. 2015 Jun 15;25(12):2555-8.
    An antibacterial ortho-quinone diterpenoid and its derivatives from Caryopteris mongolica.[Pubmed: 25958242]

    To identify antibacterial components in traditional Mongolian medicinal plant Caryopteris mongolica, an ortho-quinone abietane caryopteron A (1) and three its derivatives caryopteron B-D (2-4) were isolated from the roots of the plant together with three known abietanes demethylcryptojaponol (5), 6α-hydroxydemethyl cryptojaponol (6), and 14-Deoxycoleon U (7). The chemical structures of these abietane derivatives were elucidated on the basis of spectroscopic data. Compounds 1-4 had C-13 methylcyclopropane substructures, and 2-4 had a hexanedioic anhydride ring C instead of ortho-quinone in 1. The stereochemistry of these compound was assumed from NOE spectra and ECD Cotton effects.
    Compounds 1 and 5-7 showed antibacterial activities against the Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Micrococcus luteus, being 1 the more potent.

    Catalog No: CFN95013
    CAS No: 3968-19-2
    Price: Inquiry(manager@chemfaces.com)
    Pueroside C

    Catalog No: CFN95156
    CAS No: 112343-16-5
    Price: $368/5mg
    15-Deoxypulic acid

    Catalog No: CFN95262
    CAS No: 95523-05-0
    Price: $368/5mg
    Isosaponarin 2''-O-glucoside (Isovitexin-2''-4'-di-O-beta-D-glucoside)

    Catalog No: CFN95296
    CAS No: 63316-27-8
    Price: $318/10mg
    New compound 10

    Catalog No: CFN95343
    CAS No: N/A
    Price: $318/5mg
    Eucomic acid

    Catalog No: CFN95364
    CAS No: 42151-32-6
    Price: $368/5mg

    Catalog No: CFN95397
    CAS No: 29976-51-0
    Price: $318/5mg
    Kaempferol 3,5-O-diglucoside

    Catalog No: CFN95487
    CAS No: 205103-97-5
    Price: $318/10mg
    Oxytroflavoside B

    Catalog No: CFN95490
    CAS No: 1391144-81-2
    Price: $318/10mg
    11alpha-hydroxy-3,7-dioxo-5alpha-lanosta-8,24(E)-dien-26-oic acid

    Catalog No: CFN95592
    CAS No: 1245703-70-1
    Price: $413/5mg