11,15-Dihydroxy-16-kauren-19-oic acid
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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CHEMICAL & PHARMACEUTICAL BULLETIN, 1990, 38(5):1308-1312.
Kaurane-type diterpenes from Adenostemma lavenia O. Kuntze.[Reference:
WebLink]
METHODS AND RESULTS:
Ten 11-oxygenated kauran-19-oic acids, ent-11α, 15α-dihydroxykaur-16-en-19-oic acid(11,15-Dihydroxy-16-kauren-19-oic acid), ent-11α-hydroxy-15α-acetoxykaur-16-en-19-oic acid, ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic acid and adenostemmoic acids A-G and their nine glycosides, paniculosides II and III and adenostemmosides A-G were characterized from Adenostemma lavenia O. KUNTZE. ent-11α-Hydroxy-15-oxo-kaur-16-en-19-oic acid and adenostemmoic acid B showed cytotoxic activity against L-5178Y cultured cell and prolonged the survival of mice.
Journal of Natural Products, 1979, 42(2):183-186.
Isolation of 11-Hydroxyated Kauranic Acids From Adenostemma lavenia.[Reference:
WebLink]
METHODS AND RESULTS:
Four 11-hydroxylated kauranic acids were characterized from Adenostemma lavenia (L.) O. Kuntze, namely: ent-11α-hydroxy-15α-acetoxykaur-16-en-19-oic acid (1), ent-11α, 15α-dihydroxykaur-16-en-19-oic acid (11,15-Dihydroxy-16-kauren-19-oic acid
,2), (16R)-ent-11α-hydroxy-15-oxokauran-19-oic acid (3), and ent-11α-hydroxy-15-oxokaur-16-en-19-oic acid (4).
