Pterisolic acid A
Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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China Journal of Chinese Materia Medica, 2016, 41(24):4610-4.
Chemical constituents from Pteris multifida and cytotoxic activity[Reference:
WebLink]
METHODS AND RESULTS:
The materials were extracted by 95% ethanol,and the extracting solution was isolated by kinds of chromatographic columns including polyamide, MCI,preparative MPLC,and preparative HPLC. Eight diterpenes and two sesquiterpenes were isolated from the plant. On analysis of ESI-MS and NMR spectroscopic data,the structures were established as ent-3β-hydroxy-kaur-16-en-19-al( 1),4-epi-kaurenic acid( 2),mitrekaurenone( 3),7β,16α,17-trihydroxy-ent-kauran-19-oic acid( 4),crotonkinin E( 5),crotonkinin F( 6),Pterisolic acid A( 7),pterisolic acid C( 8),( 2R)-pterosin P( 9),and dehydropterosin B( 10).
CONCLUSIONS:
Compounds 1-6 were obtained from Pteris for the first time,and compounds 7-10 were obtained from P. ensiformis for the first time. Compounds 5-8 showed moderate activity against HCT-116,Hep G2 and BGC-823 cell lines,separately.
