ent-16-Kaurene-3beta,15beta,18-triol | CAS:921211-29-2

ent-16-Kaurene-3beta,15beta,18-triol, ent-16-kaurene-3beta,15beta-diol,abbeokutone,and helioscopinolide A possess appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.

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Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora.[Pubmed: 17095024 ]

METHODS AND RESULTS:
Two ent-kaurene diterpenes, ent-16-Kaurene-3beta,15beta,18-triol (1) and ent-3-oxo-16-kaurene-15beta,18-diol (2), were isolated from a dichloromethane extract of the bark of Suregada multiflora along with five known diterpenes:ent-16-kaurene-3beta,15beta-diol (3), abbeokutone (4), helioscopinolide A (5), helioscopinolide C (6) and helioscopinolide I (7). Their structures were elucidated on the basis of spectroscopic analysis.
CONCLUSIONS:
Compounds 1-7 possessed appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.

Product Name	ent-16-Kaurene-3beta,15beta,18-triol
CAS No.:	921211-29-2
Catalog No.:	CFN96331
Molecular Formula:	C₂₀H₃₂O₃
Molecular Weight:	320.5 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The barks of Suregada multiflora.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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