Datura metel is a shrub-like perennial herb, commonly known as angel's trumpet, devil's trumpet, and metel.
Withametelin Q (1) and 12α-hydroxydaturametelin B (2) were isolated from leaves of Daturametel L. Withanolide 2 displayed cytotoxic activity against human lung carcinoma cells (A549) and human colorectal adenocarcinoma cells (DLD-1).
The plant is an annual herb growing up to 3 ft. high. It is slightly furry, with dark violet shoots and oval to broad oval leaves that are often dark violet as well. The pleasantly-scented 6-8 in. flowers are immensely varied, and can be single or double. Colors range from white to cream, yellow, red, and violet. The seed capsule is covered with numerous conical humps and a few spines.

It is similar to D. inoxia, but D. metel has almost glabrous leaves and fruits that are knobby, not spiny. D. inoxia is pilose all over and has a spiny fruit.