Inhibitors

5-Methoxycanthin-6-one
Catalog No: CFN92362

5-Methoxycanthin-6-one displays moderate cytotoxic activity against the human prostate cancer cell PC-3 line, with IC₅₀ values ranging from 13.5-15.4 uM versus doxorubicine with IC₅₀ = 1.5 uM. It also exhibits a clear suppressive effect on the phagocytosis response upon activation with serum-opsonized zymosan in the range of IC₅₀ = 0.9-2.0 uM versus ibuprofen with IC₅₀ = 12.1 uM.

6-Hydroxykaempferol
Catalog No: CFN92370

6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.

Kushenol X
Catalog No: CFN92390

Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).

Kushenol C
Catalog No: CFN92391

Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutans. Kushenol C may be potent preventive and therapeutic candidates for Alzheimer's disease, it (IC(50) 5.45 microM) can inhibit beta-site APP cleaving enzyme 1 (BACE1) activities.

3-O-Feruloylquinic acid
Catalog No: CFN92393

3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.