Inhibitors

Skimmianin
Catalog No: CFN92555

Skimmianine is a new inhibitor against the Leishmania APRT enzyme, it is also a strong acetylcholinesterase (AChE) inhibitor. Skimmianine has anti-inflammatory, immunomodulatory, and leishmanicidal properties, it has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats.

Purpurin
Catalog No: CFN92566

Purpurin is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. Purpurin is a novel specific inhibitor of Adipocyte-derived leucine aminopeptidase, it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities.

Demethylwedelolactone
Catalog No: CFN90521

Demethylwedelolactone has trypsin inhibitory effect, it exerts anti-invasive growth effect on breast cancer cells.

Anemonine
Catalog No: CFN90524

Anemonin, a naturally occurring selective iNOS inhibitor, it has potential anti-inflammatory effect; it is also a potent protective molecule for osteoarthritis, it delays osteoarthritis progression by suppressing ECM loss and chondrocyte hypertrophy partially by suppressing IL-1β/NF-κB pathway activation. Anemonin can alleviate nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway. Anemonin inhibits melanin synthesis by inhibiting the transcription of the genes encoding MITF, TYR, TRP1, and TRP2.

Corydine
Catalog No: CFN90527

Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial fall in blood pressure followed by a return to normal or above normal.