Inhibitors

Chikusetsusaponin IV
Catalog No: CFN90542

Chikusetsusaponin IV may relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.

Methyl reserpate
Catalog No: CFN92579

1. Methyl reserpate and reserpinediol, derivatives that incorporate the alkaloid ring system, also competitively inhibit norepinephrine transport into chromaffin vesicles with Ki values of 38 +/- 10 nM and 440 +/- 240 nM, respectively.

Ganomycin I
Catalog No: CFN92595

Ganomycin I inhibits the activity of HIV-1 protease.

Sodium barbital
Catalog No: CFN00448

Sodium barbital is a depressant of the central nervous system, has sedative/hypnotic effects, it as an inhibitor of rabbit-muscle creatine kinase (CK), it might compete with both creatine and ATP, but mainly with creatine, to inhibit the activity of CK. Sodium barbital is a tumour promoter, it can shorten the otherwise long latency between exposure to toxin and tumourigenesis. Sodium barbital causes progression to the stage of spontaneous renal lesions in Tsc2 mutant rats but do not increase their overall number.

Moschamine
Catalog No: CFN94006

Moschamine is a very potent compound that is able to inhibit COX-I by 58% and COX-II by 54%, at the concentration of 0.1 μmol L⁻1, it may suppress cAMP formation via binding to 5-HT1 receptors in the cells. Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells.