7-Geranyloxy-6-methoxycoumarin

7-Geranyloxy-6-methoxycoumarin
Product Name 7-Geranyloxy-6-methoxycoumarin
CAS No.: 28587-43-1
Catalog No.: CFN98348
Molecular Formula: C20H24O4
Molecular Weight: 328.4 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Targets: HIF
Source: The herbs of Murraya tetramera Huang
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/10mg
7-Geranyloxy-6-methoxycoumarin shows significant cytotoxicity against three cell lines (A549, SMMC-7721 and BALL-1).
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Inflammation.2020, 43(5):1716-1728.
  • Journal of Ginseng Research2022, j.jgr.2022.09.005.
  • Phytomedicine.2024, 122:155065.
  • Toxicological Research2020, doi: 10.1007.
  • Nutrients2022, 14(3),695.
  • Pharmaceuticals (Basel).2024, 17(3):341.
  • Industrial Crops and Products2018, 353-362
  • Gene.2022, 815:146178.
  • Molecules2022, 27(14):4601
  • Molecules.2018, 23(7):E1817
  • 5,7-Dihydroxy-4-methylcoumarin

    Catalog No: CFN93090
    CAS No: 2107-76-8
    Price: Inquiry(manager@chemfaces.com)
    6,7-Dihydroxycoumarin

    Catalog No: CFN99115
    CAS No: 305-01-1
    Price: $30/20mg
    4-Methylesculetin

    Catalog No: CFN93058
    CAS No: 529-84-0
    Price: Inquiry(manager@chemfaces.com)
    Esculin

    Catalog No: CFN99114
    CAS No: 531-75-9
    Price: $30/20mg
    Isoscopoletin

    Catalog No: CFN97684
    CAS No: 776-86-3
    Price: $70/20mg
    Magnolioside

    Catalog No: CFN90699
    CAS No: 20186-29-2
    Price: $268/10mg
    Scopoletin

    Catalog No: CFN97494
    CAS No: 92-61-5
    Price: $30/20mg
    Scopoletin acetate

    Catalog No: CFN98951
    CAS No: 56795-51-8
    Price: Inquiry(manager@chemfaces.com)
    7-O-Prenylscopoletin

    Catalog No: CFN92639
    CAS No: 13544-37-1
    Price: Inquiry(manager@chemfaces.com)
    7-Geranyloxy-6-methoxycoumarin

    Catalog No: CFN98348
    CAS No: 28587-43-1
    Price: $318/10mg
    Molecules. 2014 Aug 27;19(9):13225-34.
    Cytotoxic compounds isolated from Murraya tetramera Huang.[Pubmed: 25165861]
    A new compound and seven known compounds were isolated from Murraya tetramera Huang for the first time, and they were identified with NMR and MS spectral analysis.
    METHODS AND RESULTS:
    It was confirmed that the new compound was 10-methoxy-7-methyl-2H-benzo[g]chromen-2-one (3) and the others were β-eudesmol (1), trans-3β-(1-hydroxy-1-methylethyl)-8aβ-methyl-5-methylenedecalin-2-one (2), 5,7-dimethoxy-8-[(Z)-3'-methyl-butan-1',3'-dienyl]coumarin (4), 7-Geranyloxy-6-methoxycoumarin (5), 5,7-dimethoxy-8-(3-methyl-2-oxo-butyl)coumarin (6), murrangatin acetate (7) and toddalenone (8). Furthermore, the cytotoxic activity against human lung adenocarcinoma (A549), human hepatocellular carcinoma cells (SMMC-7721), human bladder tumor cells (EJ), human cervical carcinoma cells (HeLa), and human B-lineage acute lymphoblastic leukemia 1 cells (BALL-1) was evaluated for all compounds. It was found that five of them displayed various degrees of cytotoxicity against different testing targets.
    CONCLUSIONS:
    Compound 1 showed significant cytotoxic activity against the five cell lines (A549, SMMC-7721, EJ, Hela and BALL-1). Compounds 2 and 5 showed significant cytotoxicity against three cell lines (A549, SMMC-7721 and BALL-1). Compound 4 showed significant cytotoxicity against three cell lines (A549, EJ and BALL-1). However, compound 3 only showed fair cytotoxicity against the BALL-1 cell line. The structure-active relationships were investigated as well. These active compounds might be potential lead compounds for the treatment of cancer.
    Suchilactone

    Catalog No: CFN95010
    CAS No: 50816-74-5
    Price: $338/5mg
    1,3,6-Trihydroxy-2-methylanthraquinone 3-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside

    Catalog No: CFN95096
    CAS No: 87686-88-2
    Price: $318/10mg
    Arisantetralone B

    Catalog No: CFN95211
    CAS No: 1161947-96-1
    Price: $413/5mg
    Isovitexin-2''-O-rhamnoside (2''-O-alpha-L-Rhamnopyranosyl-isovitexin)

    Catalog No: CFN95314
    CAS No: 72036-50-1
    Price: $368/10mg
    Peiioside B

    Catalog No: CFN95336
    CAS No: 1610618-91-1
    Price: $318/5mg
    Fuzitine

    Catalog No: CFN95337
    CAS No: 142287-96-5
    Price: $318/5mg
    Euphorbia factor L22

    Catalog No: CFN95338
    CAS No: 1613700-09-6
    Price: $413/5mg
    Foliachinenoside C

    Catalog No: CFN95361
    CAS No: 1041180-87-3
    Price: $368/5mg
    Massonianoside D

    Catalog No: CFN95500
    CAS No: 85115-04-4
    Price: $318/10mg
    3',3'''-Binaringenin

    Catalog No: CFN95558
    CAS No: 145399-99-1
    Price: $413/5mg