Analgesia

Salvigenin
Catalog No: CFN99883

Salvigenin, a potent hMAO-A [monoamine oxidases (MAOs)]inhibitor, has neuroprotective, antitumor and immunomodulatory effects, it has potential to ameliorate Streptozotocin-induced diabetes mellitus and heart complications in rats. Salvigenin has dose-dependent analgesic effect so that it can be useful in controlling of inflammations, acute and chronic pain.

Ligustilide
Catalog No: CFN99932

Ligustilide possesses neuroprotective, vasorelaxation, antinociceptive and anti-inflammatory activities, it blocked the activation of MAPKs/IKK and the downstream transcription factors AP-1 and NF-κB. It has the potential to be developed into an effective drug for the treatment of various pain syndromes including primary dysmenorrhoea.

Bavachinin
Catalog No: CFN98006

Bavachinin is a novel natural pan-PPAR agonist , it shows stronger activities with PPAR-γ than with PPAR-α and PPAR-β/δ (EC50 = 0.74 μmol/l, 4.00 μmol/l and 8.07 μmol/l in 293T cells, respectively). Bavachinin possesses anti-asthma, anti-angiogenic , anti-inflammatory, antipyretic and analgesic properties, it also exhibits glucose-lowering properties without inducing weight gain and hepatotoxicity.

Gentiopicroside
Catalog No: CFN98047

Gentiopicroside has been developed into a novel traditional Chinese drug named gentiopicroside injection, and it was approved for the treatment of acute jaundice and chronic active hepatitis by SFDA.Gentiopicroside has analgesic, smooth muscle relaxing, antibacterial, and free radical scavenging activities, it exerts anti-inflammatory effects on experimental acute colitis through attenuating the expression levels of TNF-α, IL-1β, IL-6, iNOS and COX-2.

Magnoflorine
Catalog No: CFN98071

Magnoflorine possesses high activity as α-glucosidase inhibitor in vitro and in vivo, has antidiabetic potential activity; it also has sedative and anxiolytic effects, probably mediated by a GABAergic mechanism of action. Magnoflorine has protective effects, mediated by some mechanism other than prevention of micelle formation or protection of the erythrocyte membrane against osmotic imbalance.