Hypotaurine
Catalog No: CFN00019
Hypotaurine is a precursor of taurine and an antioxidant, intracellular hypotaurine is mainly supplied to placental trophoblasts by transfer from extracellular fluid across the plasma membrane, and may play a role in cell protection by scavenging reactive oxygen species.
Hypotaurine also suppresses acute, inflammatory, and neuropathic pain, may regulate nociceptive transmission physiologically by activating glycinergic neurons in the spinal cord, is a promising candidate for treating various pain states.Hypotaurine/taurine synthesis strongly inhibits cysteinesulfinate decarboxylase (pyridoxal 5'-phosphate-dependent enzyme) as well as cystathionine γ-lyase. Hypotaurine and raffinose supplementation in semen extenders provide a protection of sperm parameters against cryopreservation injury.
Kirenol
Catalog No: CFN98867
Kirenol possesses anti-bacteria, immunosuppression, anti-obesity, anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. Kirenol has significant potential for its discovery as a new lead compound for management of topical pain and inflammation; it can upregulate nuclear Annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats. Kirenol can attenuate experimental autoimmune encephalomyelitis by inhibiting differentiation of Th1 and th17 cells and inducing apoptosis of effector T cells. Kirenol activates the BMP and Wnt/β-catenin signaling pathways.