Hot Products

Yuexiandajisu D
Catalog No: CFN92874

Yuexiandajisu D is slightly active against ANA-1 cells with an IC50 value 2.88 x 10(-1)microM. It shows moderate cytotoxic activity against cancer cell lines on HCT-8 and Bel-7402, with IC50 values of 2.66 and 3.76 microM, respectively.

Yuexiandajisu E
Catalog No: CFN92875

Standard reference

Yukovanol
Catalog No: CFN92795

Yukovanol inhibits the proliferation of activated HSC-T6 cells in vitro.

Yunaconitine
Catalog No: CFN99503

Yunaconitine has anti-inflammatory and analgesic actions. It can increase serum total complement as well as the phag-ocytic activity of reticuloendothelial system in mice, these effects are considered to be beneficial in the clearance of pathogenic antigens, and may be the immunopharmacological basis of antiinflammatory actions of yunaconitine.

Zearalenone
Catalog No: CFN91172

Zearalenone is one of the most widely distributed harmful mycotoxins produced by Fusarium species, especially deposited in corn oil. Zearalenone has been shown to cause diverse toxic effects in animals and are also suspected of disease causation in humans. It and its phase I metabolites α- and ß-zearalenol are also HSP90 ATPase inhibitors.

Zeaxanthin
Catalog No: CFN90234

Lutein and Zeaxanthin in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. Lutein and Zeaxanthin may be protective against eye disease because they absorb damaging blue light that enters the eye.

Zederone
Catalog No: CFN92616

Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries.

Zedoarondiol
Catalog No: CFN92652

Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway. It dose-dependently inhibits LPS-stimulated nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1beta (IL-1beta) productions in RAW 264.7 macrophage and in mouse peritoneal macrophage cells.

Zerumbone
Catalog No: CFN91066

Zerumbone is a potential antimicrobial and antibiofilm agent indicated for the therapeutic management of nosocomial medical device-related infections induced by dual-species biofilms of C. albicans and S. aureus. Zerumbone protects the neuronal injury and ameliorates the cognitive function by stimulating the proliferation of endogenous neural stem cells; it suppresses enterotoxigenic bacteroides fragilis infection-induced colonic inflammation through inhibition of NF-κΒ. Zerumbone exhibits a hepatoprotective effect against ALI through its antioxidant and anti-inflammatory activities and the possible mechanism might be mediated by the TLR4/NF-κB/COX-2 pathway. Zerumbone can be a potential candidate for development of immunosuppressive agent.

Zingerone
Catalog No: CFN99702

Zingerone has anti-mutagenic, anti-carcinogenic, anti-obesity,anti-oxidative and anti-inflammatory activities. Zingerone can be recommended as a supplement to shrimp feed to increase growth, immunity, and disease resistance against the pathogen, V.alginolyticus , use of zingerone as appetizer and immunostimulant in shrimp is promising. It could as potential phytotherapeutic agent which in future can be employed to formulate preventive strategies against biofilm associated infections caused by P.aeruginosa.