Thamnosmonin
Thamnosmonin is a natural product from Citrus sinensis.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Pharmacol Rep.2022, 74(1):175-188.
Applied Biological Chemistry2023, 66:42.
Front. Physiol.2022, 790345.
Biomed Chromatogr.2019, 8:e4774
Biomed Pharmacother.2022, 146:112497.
The Korea Journal of Herbology2016, 29-35
Biomed Pharmacother.2023, 163:114785.
Chem Biodivers.2023, 20(10):e202300741.
Molecular & Cellular Toxicology2017, 13(3):271-278
Molecules.2024, 29(6):1240.
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Phytother Res. 2007 Apr;21(4):386-90.
Modulation of P-glycoprotein activity by acridones and coumarins from Citrus sinensis.[Pubmed:
17236173 ]
METHODS AND RESULTS:
Bioguided fractionation of the roots of Citrus sinensis (Rutaceae) led to the isolation and identification of five coumarins, namely, clausarin, suberosin, poncitrin, xanthyletin and Thamnosmonin, seven acridones, namely, acrimarine B, 2-methoxycitpressine I, citpressine I, buntanine, acrimarine E, honyumine and acrimarine C, and one terpenoid, namely, limonin.
CONCLUSIONS:
Among these compounds, clausarin, 2-methoxycitpressine I and acrimarine E inhibited P-glycoprotein-mediated drug efflux in K562/R7 human leukemic cells over-expressing P-glycoprotein.
Zhong Yao Cai. 2013 May;36(5):744-6.
Study on the chemical constituents from ethyl acetate extract of Micromelum falcatum.[Pubmed:
24218965]
To study the chemical constituents from ethyl acetate extract of Micromelum falcatum.
METHODS AND RESULTS:
The constituents were separated and purified by silica gel, Sephadex LH-20 and HPLC. Their structures were elucidated by spectral analysis (NMR, MS).
Ten compounds were isolated and identified as micropubescin (1), phebalosin (2), scopoletin (3), citrubuntin (4), Thamnosmonin (5), hopeyhopin (6), arnottinin (7), casegravol (8), 2-methoxy-5-hydroxy cinnamate (9), threo-syringoylglycerol (10).
CONCLUSIONS:
Compounds 1 - 10 are obtained from this plant for the first time.
