Toddanone

Toddanone
Product Name Toddanone
CAS No.: 77636-08-9
Catalog No.: CFN92514
Molecular Formula: C16H18O5
Molecular Weight: 290.3 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Cryst.
Source: The roots of Toddalia asiatica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Phytother Res. 2002 May;16(3):281-2.
    Spasmolytic activity of Toddalia asiatica Var. floribunda.[Pubmed: 12164278]

    METHODS AND RESULTS:
    The spasmolytic activity of the aerial parts of Toddalia asiatica var. floribunda (family Rutaceae) was evaluated. The ethanol extract exhibited significant spasmolytic activity and was then partitioned into five fractions. The activity was found to be concentrated only in the hexane and chloroform fractions.
    CONCLUSIONS:
    This activity was shown not to be due to the coumarins, toddalolactone and Toddanone, as was previously thought.
    Huria Journal of the Open University of Tanzania, 2012 , 12 (1).
    Antifeedant activity of twenty six plant extracts and pure compounds from the root bark of Toddalia asiatica (L) (Rutaceae) against the anomalous emperor moth Nudaurelia belina (Saturnidae)[Reference: WebLink]
    The antifeedant activity of petroleum ether (PE) (40-60%) extract of the root bark of T. asiatica and twenty five other plant extracts was investigated against the anomalous emperor moth N. belina.
    METHODS AND RESULTS:
    The petroleum ether extract of stem bark of Albizia anthelmintica, leaves of Cassia occidentalis, Balanites aegyptica, seeds of Cucumis sativaus, root bark of T. asiatica, root bark of Celtis durandii, B. aegyptica and whole plant of Cisus quadrangularis were found to be active against N. belina at a concentration of 1% w/v in a modified leaf disc method. Also, methanol extracts of the root bark of A. muricata and Eucalyptus spp were found to be active against N. belina at a concentration of 1% w/v.
    CONCLUSIONS:
    Three cumarius; dihydrotoddanol, toddanol and toddalactone and the alkaloid dihydrochelerynthrine isolated from the PE extract of the root bark of T. asiatica exhibited antifeedant activity at as low as 0.05% w/v. Toddaculine and Toddanone which were also isolated from the P.E. extract had no activity at 0.05% w/v.
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