Rubicordifolin
Rubicordifolin exhibits potent cytotoxic and antitumor activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Sci Rep. 2018, 10590
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Korean Chemical Society National Meeting October. 2015.
Re2O7-Catalyzed Regioselective Synthesis of Naphtho[1,2-b]furan-3-carboxamides and Their Biological Evaluation[Reference:
WebLink]
METHODS AND RESULTS:
Rubicordifolin was isolated as a natural product from Rubia cordifolia, and it exhibits potent cytotoxic and antitumor activities. Furomollugin has been isolated from several members of the Rubiaceae family and from Rubia cordifolia.
CONCLUSIONS:
The compound exhibits cytotoxic activity to human colon carcinoma cells (HT-29), strongly suppresses HBsAg secretion by human hepatoma Hep3B cells, and exhibits inhibitory activity against DNA topoisomerases I and II.
J Am Chem Soc. 2005 Mar 9;127(9):2870-1.
Biomimetic synthesis and structure elucidation of rubicordifolin, a cytotoxic natural product from Rubia cordifolia.[Pubmed:
15740120 ]
The biomimetic synthesis and full structural elucidation of Rubicordifolin, a cytotoxic natural product isolated from Rubia cordifolia, is described.
