Rengynic acid
Rengynic acid has potent antiviral effect on RSV for the first time in vitro.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J AOAC Int.2021, 104(6):1634-1651.
Journal of Food Composition and Analysis2021, 100:103905.
Natural Product Communications2020, doi: 10.1177.
J Pharmacol Sci.2021, 147(2):184-191.
Phytother Res.2019, 33(3):676-689
Phytomedicine.2023, 116:154841.
J Ethnopharmacol.2024, 320:117426.
Evid Based Complement Alternat Med.2022, 9767292,2.
Separations2021, 8(1), 1.
Bioorg Chem.2024, 150:107558.
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J Asian Nat Prod Res. 2014;16(4):376-82.
Two new glycosides from the fruits of Forsythia suspense.[Pubmed:
24506327]
METHODS AND RESULTS:
Two new glycosides suspensaside C (1) and 2,3,5,6-tetrahydro-jacaranone-4-O-β-D-glucopyranoside (2), together with four known compounds suspensaside A (3), Rengynic acid-1'-O-β-D-glucopyranoside (4), forsythoside A (5), and Rengynic acid (6), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HR-ESI-MS.
All isolates were tested for their cytotoxicities against five human cancer cell lines (A549, Colo-205, Hep-3B, HL60, and KB).
CONCLUSIONS:
Compound 3 exhibited cytotoxicity against HL-60, Hep-3B, and A549 cancer cell lines.
J Herb Pharmacother. 2002;2(3):35-40.
A new compound from Forsythia suspensa (Thunb.) Vahl with antiviral effect on RSV.[Pubmed:
15277088]
METHODS AND RESULTS:
A new compound, 2-(1,4-dihydroxy cyclohexanyl )-acetic acid isolated from the seeds of Forsythia suspensa (Thunb.) Vahl, has been assessed for potent antiviral effect on RSV for the first time in vitro by cell morphology methods.
CONCLUSIONS:
Its structure was elucidated on the basis of spectroscopic evidence (IR, MS, 1H-NMR, 13C-NMR). We have trivially named it Rengynic acid.
