Physarorubinic acid A
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Natural Product Communications2020, doi: 10.1177.
Mol Microbiol.2019, 112(1):317-332
Chem. of Vegetable Raw Materials2020, 97-105
J Cell Mol Med.2023, 27(11):1592-1602.
Mol Pharm.2017, 14(9):3164-3177
Separations2021, 8(7),90.
Phytomedicine.2018, 38:45-56
Front Plant Sci.2022, 13: 905275.
J Chromatogr Sci.2015, 53(5):824-9
Front Plant Sci.2021, 12: 648426.
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Journal of the Chemical Society, Perkin Transactions 1, 1999(16):2231-2232.
Total Synthesis of the Plasmoidal Pigment Physarorubinic Acid, a Polyenoyl Tetramic Acid.[Reference:
WebLink]
METHODS AND RESULTS:
The total synthesis of physarorubinic acid, a polyenoyltetramic acid plasmoidal pigment from Physarum polycephalum, is described in a series of steps from (E)-3-iodoacrylic acid 6 and employs aminolysis of the pentaene thioester 11 as a key synthetic step. Lacey–Dieckmann cyclisation and subsequent deprotection then affords physarorubinic acid 1 in high yield and purity.
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