Paprazine
Paprazine may have cytotoxic activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytochemistry Letters2015, 243-247
Indian J Pharm Sci.2022, 84(3):144-151
Neurochem Int.2018, 121:114-124
Eur J Pharmacol.2024, 981:176883.
J Ethnopharmacol.2024, 318(Pt B):116961.
Cell Death Differ.2021, 1-8.
Food Bioscience2023, 59:103903
Neurotoxicology.2022, 91:218-227.
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Zhongguo Zhong Yao Za Zhi. 2018 Apr;43(8):1654-1661.
Chemical constituents from roots of Datura metel.[Pubmed:
29751713]
To study the flavonoids of Scutellaria baicalensis and their bioactivities.
METHODS AND RESULTS:
Chromatographic methods were used to separate compounds, spectral methods were used to determine the structures and bioactivities of the flavonoids were screened in several models in vitro.
Nine compounds were isolated and identified as baicalein (1), wogonin (2), oroxylin A (3), 5, 7, 2', 6'-tetrahydroxyflavone (4), viscidulin III (5), baicalin (6), wogonoside (7), oroxylin A-7-O-beta-D-glucuronide (8) and chrysin-6-C-alpha-L-arabinopyranosyl-8-C-beta-D-glucopyranoside (9).
CONCLUSIONS:
Baicalein had good anti-bacteria activity, and some compounds showed inhibiting activity against IL-1beta converting enzyme. The 13C NMR data of compounds 9 were assigned correctly by 2D nuclear magnetic resonance (NMR).
Nat Prod Res. 2009;23(15):1416-23.
Alkaloids from Piper sarmentosum and Piper nigrum.[Pubmed:
19809914 ]
Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids.
METHODS AND RESULTS:
The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). Piper nigrum roots gave pellitorine (2), (E)-1-[3',4'-(methylenedioxy)cinnamoyl]piperidine (3), 2,4-tetradecadienoic acid isobutyl amide (4), piperine (5), sylvamide (6), cepharadione A (7), piperolactam D (8) and Paprazine (9). Structural elucidation of these compounds was achieved through NMR and MS techniques.
CONCLUSIONS:
Cytotoxic activity screening of the plant extracts indicated some activity.
