Olivil

Olivil
Product Name Olivil
CAS No.: 2955-23-9
Catalog No.: CFN98365
Molecular Formula: C20H24O7
Molecular Weight: 376.4 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The roots of Valeriana officinalis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
(-)-Olivil displays a higher antioxidative effect against the free radical DPPH.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J.Acta Agriculturae Scandinavica2017, 571-575
  • Front Pharmacol.2018, 9:236
  • Mol Pharmacol.2021, 99(2):163-174.
  • J Biochem Mol Toxicol.2020, 34(7):e22489.
  • Evid Based Complement Alternat Med.2021, 2021:8707280.
  • Cell.2022, 185(23):4298-4316.e21.
  • Nanotechnology.2024, ad470d.
  • United States Patent Application2020, 20200038363
  • J Nat Med.2022, 76(1):59-67.
  • Front Pharmacol.2020, 11:251.
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    J Agric Food Chem. 2014 Jan 8;62(1):144-51.
    Radical-scavenging compounds from olive tree (Olea europaea L.) wood.[Pubmed: 24328093]
    The purpose of this study was to complete knowledge on the chemical composition and radical-scavenging activity of olive tree wood.
    METHODS AND RESULTS:
    Two new monoterpene glycosides, (-)-oleuropeic acid 6'-O-α-D-glucopyranosyl ester (6a) and (-)-perillic acid 1'-O-β-D-primeverosyl ester (8), together with the known compounds (-)-oleuropeic acid (1), (-)-Olivil (2), the aldehydic form of oleuropein aglycone (3), (+)-1-hydroxypinoresinol 1-O-β-D-glucopyranoside (4), (-)-oleuropeic acid 1'-O-β-D-glucopyranosyl ester (5), (-)-oleuropeic acid 6'-O-β-D-glucopyranosyl ester (6b), and (-)-Olivil 4-O-β-D-glucopyranoside (7) were isolated from an ethyl acetate extract. The radical scavengers found (2-4 and 7) were detected and isolated with the help of the online HPLC-DAD-DPPH/ABTS technique.
    CONCLUSIONS:
    Compounds 2-4 and 7 displayed a higher antioxidative effect against the free radical DPPH than the reference BHT and lower than hydroxytyrosol, whereas compounds 1, 5, 6a, 6b, and 8 showed no activity.
    Biosci Biotechnol Biochem. 2003 Feb;67(2):415-9.
    (-)-olivil and (+)-1-acetoxypinoresinol from the olive tree (Olea europaea Linne; Oleaceae) as feeding stimulants of the olive weevil (Dyscerus perforatus).[Pubmed: 12729011]

    METHODS AND RESULTS:
    Guided by a feeding stimulant activity test on the olive weevil (Dyscerus perforatus), two compounds that showed potent feeding stimulant activity were isolated from the olive tree (Olea europaea). Based on their spectral data and a literature survey, they were identified as (-)-Olivil (1) and (+ )-1-acetoxypinoresinol (2).
    CONCLUSIONS:
    The activities of these minor lignans were significantly higher for the female than for the male weevil.
    Biosci Biotechnol Biochem. 2005 Jan;69(1):113-22.
    Synthesis and antioxidant activity of olivil-type lignans.[Pubmed: 15665475]

    METHODS AND RESULTS:
    Olivil-type lignans, an enantiomeric type of natural Olivil, were synthesized for the first time to evaluate the relationship between the structure of Olivil and its antioxidant activity. A comparison of the antioxidant activity with that of other synthesized tetrahydrofuran lignans indicated reduced activity with the tertiary hydroxy group.
    CONCLUSIONS:
    A different effect of the two phenolic groups of Olivil on the antioxidant activity was also observed.
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