Product Name 9-O-Feruloyl-5,5'-dimethoxylariciresinol
CAS No.: 166322-14-1
Catalog No.: CFN99700
Molecular Formula: C32H36O11
Molecular Weight: 596.6 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Targets: TNF-α | IL Receptor
Source: The herbs of Viburnum cylindricum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Institut Pasteur Korea2020, doi: 10.21203.
  • Cosmetics2021, 8(3),91.
  • Chemistry of Natural Compounds2018, 204-206
  • Institute of Food Science & Technology2021, 18 December.
  • J of Physics Conference Series2019, 1349(1)
  • Food Analytical Methods2020, 13,1603-1612(2020)
  • VNU Journal of Science2023, No. 20.
  • Plant Biotechnology Reports 2021, 15:117-124.
  • Neurochem Res.2021, s11064-021-03449-0
  • J Ethnopharmacol.2022, 291:115159.
  • Massoniresinol

    Catalog No: CFN97541
    CAS No: 96087-10-4
    Price: Inquiry(manager@chemfaces.com)
    Olivil monoacetate

    Catalog No: CFN97860
    CAS No: 1016974-78-9
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN95027
    CAS No: 128855-64-1
    Price: $318/20mg

    Catalog No: CFN95031
    CAS No: 449172-61-6
    Price: $413/5mg

    Catalog No: CFN96706
    CAS No: 105256-12-0
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN92502
    CAS No: 136051-41-7
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN89318
    CAS No: 218901-26-9
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN99265
    CAS No: 116498-58-9
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN99700
    CAS No: 166322-14-1
    Price: Inquiry(manager@chemfaces.com)
    5,5'-Dimethoxylariciresinol 4-O-glucoside

    Catalog No: CFN99647
    CAS No: 154418-16-3
    Price: Inquiry(manager@chemfaces.com)
    Arch. Pharm. Res.,2014 Apr;37(4):467-72.
    A new neolignan and lignans from the stems of Lindera obtusiloba Blume and their anti-allergic inflammatory effects.[Pubmed: 24014307 ]

    A new neolignan, linderin A (1), together with six known lignans, (+)-xanthoxyol (2), pluviatilol (3), actiforin (4), (+)-syringaresinol (5), (+)-(7S,8R,8'R)-acuminatolide (6), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (9-O-Feruloyl-5,5'-dimethoxylariciresinol,7) were isolated from the stems of Lindera obtusiloba Blume (Lauraceae). Their chemical structures were elucidated by a combination of spectroscopic analysis and chemical reaction, and the absolute configuration of 1 was determined by Mosher's esterification. The effect of compounds 1-7 on tumor necrosis factor (TNF)-α, interleukin(IL)-6, and their inhibitory activity of histamine release were examined using human mast cells. Among the lignans tested, compounds 1, 3, 4, 6, and 7 inhibited release of histamine from mast cells. Especially, compounds 1 and 4 suppressed the gene expressions of pro-inflammatory cytokines, TNF-α, and IL-6 in human mast cells.
    Our findings suggest that the lignan constituents in L. obtusiloba may contribute to its anti-allergic inflammatory effects.
    Arch Pharm Res. 1999 Aug;22(4):417-22.
    Two new lignans from Lindera obtusiloba blume.[Pubmed: 10489885]

    Two new furanolignans (3, 5), together with three known lignans (1, 2, 4), were isolated from the stem of Lindera obtusiloba (Lauraceae). The structures of the compounds were determined as actifolin (1), pluviatilol (2), 5,6-dihydroxymatairesinol (3), (+)-syringaresinol (4), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (9-O-Feruloyl-5,5'-dimethoxylariciresinol,5) on the basis of physicochemical and spectroscopic evidences.
    Compounds 1, 2, 3, and 5 showed cytotoxicity against a small panel of human tumor cell lines with ED50 values of 3.40 to approximately 19.27 microg/ml.

    Catalog No: CFN95013
    CAS No: 3968-19-2
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN95024
    CAS No: 486-63-5
    Price: $288/5mg
    20-O-Glucoginsenoside Rf

    Catalog No: CFN95036
    CAS No: 68406-27-9
    Price: $318/5mg
    Stevia impurity (13-[(2-O-6-deoxy-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid beta-D-glucopyranosyl ester)

    Catalog No: CFN95229
    CAS No: 1309929-72-3
    Price: $463/5mg
    Daucoidin A

    Catalog No: CFN95275
    CAS No: 103629-87-4
    Price: $318/5mg
    Meliotocarpan D

    Catalog No: CFN95401
    CAS No: 83013-81-4
    Price: $413/5mg
    Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether

    Catalog No: CFN95416
    CAS No: 74474-55-8
    Price: $318/5mg

    Catalog No: CFN95476
    CAS No: 10240-16-1
    Price: $318/10mg
    Kihadanin D

    Catalog No: CFN95482
    CAS No: 2770024-83-2
    Price: $413/5mg
    Ganoderic acid GS-1

    Catalog No: CFN95571
    CAS No: 1206781-64-7
    Price: $413/5mg