Oleonuezhenide
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Metabolites2023, 13(1), 3.
Molecules.2019, 24(7):E1290
Molecules.2020, 25(18):4283.
AMB Express2020. 10(1):126.
Heliyon.2024, 10(7):e28755.
Evid Based Complement Alternat Med.2021, 2021:8707280.
Separations2021, 8(6),80.
Front Neurosci.2019, 13:1091
J Agric Food Chem.2023, 71(47):18510-18523.
ACS Omega.2024, 9(12):14356-14367.
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Planta Med. 2010 Jul;76(10):998-1003.
New secoiridoid glucosides from Ligustrum lucidum induce ERK and CREB phosphorylation in cultured cortical neurons.[Pubmed:
20143293]
METHODS AND RESULTS:
Two new secoiridoid glucosides, namely iso-Oleonuezhenide (1) and methyloleoside 7-ethyl ester (2), along with five known ones, Oleonuezhenide (3), nuezhenide (4), oleuropein (5), G13 (6), and jaspolyside methyl ester (7), were isolated from the fruits of Ligustrum lucidum. Their structures were assigned based on 1H-NMR, 13C-NMR, and 2D-NMR analyses, in combination with HR-MS experiments and the comparison with literature data of related compounds, as well as on chemical experiments.
CONCLUSIONS:
We have examined the ability of these compounds to activate ERK and CREB in cultured cortical neurons.
