Oleaside A
Oleaside A is a natural product from Nerium oleander.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Front Pharmacol. 2024, 15:1527494.
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Metabolites2023, 13(1), 3.
FEBS Lett.2015, 589(1):182-7
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Helvetica Chimica Acta, 2014 , 97 (2) :290-7.
Biotransformation of Oleaside A by Cunninghamella echinulata.[Reference:
WebLink]
Biotransformation of Oleaside A (1) by Cunninghamella echinulata (ACCC 30369) was carried out to afford two products, (6R)‐6‐hydroxyOleaside A (2) and (7S)‐7‐hydroxyOleaside A (3).
METHODS AND RESULTS:
The structures of 2 and 3 were elucidated by extensive NMR analyses and further confirmed by single‐crystal X‐ray diffraction analysis. We also report herein the X‐ray diffraction structure of Oleaside A (1) for the first time. Compounds 1–3 were evaluated for their cytotoxic activities against the A549, HCT116, HepG2, and HL‐60 human cancer cell lines.
Phytochemistry,1983 ,22(10) :2211-4.
Quantitative variations in the cardiac glycosides of oleander.[Reference:
WebLink]
METHODS AND RESULTS:
Cardiac glycosides of the leaves from 20 horticultural and wild strains of Nerium were examined quantitatively. The plants investigated fall into two groups based on their contents of adynerin and Oleaside A, or gentiobiosyl adynerin and oleaside E.
CONCLUSIONS:
A large variation in oleandrin content was noted in all samples.
