Odoroside H

Odoroside H
Product Name Odoroside H
CAS No.: 18810-25-8
Catalog No.: CFN99868
Molecular Formula: C30H46O8
Molecular Weight: 534.7 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Targets: Sodium Channel | ATPase | Potassium Channel
Source: The herbs of Nerium indicum
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price:
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Jurnal Ilmu Pertanian Indonesia2023, 28(4):525-533.
  • Life Sci.2021, 286:120019.
  • Plants (Basel).2021, 10(2):278.
  • Plants (Basel).2021, 10(11):2317.
  • Journal of Holistic Integrative Pharmacy2024, 5(1):45-55.
  • J Biochem Mol Toxicol.2022, e23211.
  • Int J Nanomedicine.2024, 19:1683-1697.
  • Microb Pathog.2019, 131:128-134
  • Korean Journal of Pharmacognosy2019, 50(4):285-290
  • Plant Cell,Tissue & Organ Culture2016, 127(1):115-121
  • Cymarin

    Catalog No: CFN70386
    CAS No: 508-77-0
    Price: Inquiry(manager@chemfaces.com)
    Convallatoxin

    Catalog No: CFN70385
    CAS No: 508-75-8
    Price: Inquiry(manager@chemfaces.com)
    k-Strophanthoside

    Catalog No: CFN70338
    CAS No: 33279-57-1
    Price: Inquiry(manager@chemfaces.com)
    Deslanoside

    Catalog No: CFN91787
    CAS No: 17598-65-1
    Price: $70/10mg
    Lanatoside C

    Catalog No: CFN96196
    CAS No: 17575-22-3
    Price: $108/20mg
    Periplocymarin

    Catalog No: CFN93081
    CAS No: 32476-67-8
    Price: Inquiry(manager@chemfaces.com)
    Periplocin

    Catalog No: CFN90513
    CAS No: 13137-64-9
    Price: $80/20mg
    Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside]

    Catalog No: CFN90985
    CAS No: 1253421-94-1
    Price: $268/10mg
    Digitoxin

    Catalog No: CFN98535
    CAS No: 71-63-6
    Price: $70/20mg
    Digoxin

    Catalog No: CFN98536
    CAS No: 20830-75-5
    Price: $30/20mg
    J Ethnopharmacol. 2011 Apr 12;134(3):781-8.
    Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum.[Pubmed: 21291990]
    For identification of the active constituents we investigated the anticancer activity of cardenolides from Streptocaulon tomentosum Wight & Arn. (Asclepiadaceae) and from Nerium oleander L. (Apocynaceae) which are both used against cancer in the traditional medicine in their region of origin.
    METHODS AND RESULTS:
    The antiproliferative activity of cardenolides isolated from roots of Streptocaulon tomentosum (IC(50)<1-15.3 μM after 2 days in MCF7) and of cardenolide containing fractions from the cold aqueous extract of Nerium oleander leaves ("Breastin", mean IC(50) 0.85 μg/ml in a panel of 36 human tumor cell lines), their influence on the cellular viability and on the cell cycle (block at the G2/M-phase or at the S-phase in tumor cells, respectively) were determined using different cell lines. The murine cell line L929 and normal non-tumor cells were not affected. Bioactivity guided fractionation of Breastin resulted in the isolation of the monoglycosidic cardenolides oleandrine, oleandrigeninsarmentoside, neritaloside, Odoroside H, and odoroside A (IC(50)-values between 0.010 and 0.071 μg/ml).
    CONCLUSIONS:
    The observed anticancer activities of extracts and isolated cardenolides are in agreement with the ethnomedicinal use of Streptocaulon tomentosum and Nerium oleander. The most active anticancer compounds from both species are monoglycosidic cardenolides possessing the 3β,14β-dihydroxy-5β-card-20(22)-enolide structure with or without an acetoxy group at C-16. The results indicate that the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
    Phytochemistry. 1999 Feb;50(3):435-8.
    Bio-active cardenolides from the leaves of Nerium oleander.[Pubmed: 9933955]

    METHODS AND RESULTS:
    A bioactivity directed isolation of the methanolic extract of the fresh, uncrushed leaves of Nerium oleander showing a central nervous system (CNS) depressant effect in mice has been undertaken. As a result, four CNS depressant cardenolides including a new cardenolide, neridiginoside and three known constituents, nerizoside, neritaloside and Odoroside H, have been isolated which exhibited CNS depressant activity in mice at a dose of 25 mg/kg. The structure of neridiginoside was elucidated as 3 beta-O-(D-diginosyl)-5 beta, 14 beta-dihydroxy-card-20(22)-enolide, using spectroscopic methods including one-dimensional and two-dimensional NMR (COSY-45, NOESY, J-resolved, HMQC and HMBC).
    CONCLUSIONS:
    The known compounds have been indentified through spectral studies and comparison of data with those reported in the literature.
    Lappaol A

    Catalog No: CFN95067
    CAS No: 62333-08-8
    Price: $333/10mg
    8-Hydroxypinoresinol diglucoside

    Catalog No: CFN95083
    CAS No: 112747-99-6
    Price: $318/5mg
    Rhamnocitrin 3-glucoside

    Catalog No: CFN95134
    CAS No: 41545-37-3
    Price: $318/10mg
    3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside

    Catalog No: CFN95228
    CAS No: 51768-39-9
    Price: $413/5mg
    Fortunellin-6''-beta-D-glucopyranoside (Acacetin-7-O-[2''-O-rhamnosyl-6''-O-glucosyl]-glucoside)

    Catalog No: CFN95315
    CAS No: 1218774-64-1
    Price: $318/5mg
    New compound 9

    Catalog No: CFN95342
    CAS No: N/A
    Price: $413/5mg
    Hydroxytyrosol 1-O-glucoside

    Catalog No: CFN95367
    CAS No: 76873-99-9
    Price: $318/10mg
    3',8-Dihydroxyvestitol

    Catalog No: CFN95384
    CAS No: 122587-87-5
    Price: $413/5mg
    Senkyunolide N

    Catalog No: CFN95449
    CAS No: 140694-58-2
    Price: $318/10mg
    Methyl ganoderenate B

    Catalog No: CFN95534
    CAS No: N/A
    Price: $413/5mg