Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Planta Medica, 2012, 78(11):1204-1204.
New cromones from Cnidium monnieri fruits inhibit adipocyte differentiation in 3T3-L1 cells.[Reference:
WebLink]
METHODS AND RESULTS:
Seven new chromone glycosides, monnieriside A (3),monnieriside B (10), monnieriside C (12) monnieriside D (13), monnieriside E (15), monnieriside F (16), Monnieriside G (17) and one new phenolic compound, methylpicraquassioside B (23) were isolated from the n-BuOH soluble fraction of Cnidium monnieri fruits (Umbelliferae), together with fourteen known compounds, undulatoside A (1), cnidimol C (2), saikochromoside A (4), cnidimoside A (5), cnidimoside B (6), 2-methyl-5-hydroxy-6-(2-butenyl-3-hydroxymethyl)-7-(β-D-glucopyranosyloxy)-4H-1-benzopyran-4-one (7), cnidimol D (8), hydroxycnidimoside A (9), umtatin (11), 6′-hydroxylangelicain (14), cnidioside A (18), cnidioside B (19), picraquassioside A (20), methylpicraquassioside A (21) and picraquassioside B (22). The structures of isolated compounds were determined on the basis of spectroscopic analysis including 1D, 2D NMR and HRESI-MS.
CONCLUSIONS:
Among the compounds isolated, compounds 5, 6, 9 and 10 significantly inhibited adipocyte differentiation as measured by fat accumulation in 3T3-L1 cells using Oil Red O staining.