Marrubiin
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Pharmaceutics.2021, 13(2):187.
Appl. Sci.2020, 10(23), 8729
Acta Pharmaceutica Hungarica2016, 86:35-40
Food Bioscience2023, 53:102687
Reprod Sci.2022,10.1007/s43032-022-01117-4.
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Biochemical Systematics and Ecology2018, 81
Nat Commun.2023, 14(1):4540.
Mol Cell.2017, 68(4):673-685
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Plant Growth Regulation,2008, 56(1):71-76.
Accumulation of the labdane diterpene Marrubiin in glandular trichome cells along the ontogeny of Marrubium vulgare plants.[Reference:
WebLink]
METHODS AND RESULTS:
The content of the diterpene Marrubiin was assessed by GC-FID in leaves of Marrubium vulgare plants along their ontogeny. Maximum accumulation occurred just before flowering time and in fully expanded leaves. After feeding the plants with radio labeled [3H]-geranyl geranyl diphosphate, up to 70% of the radioactivity was recovered in HPLC-Rt coincidental with authentic Marrubiin, which was also characterized by GC-EIMS, thus confirming that the biosynthesis of Marrubiin proceeds through the 1-deoxy-D-xylulose-5-phosphate pathway.
CONCLUSIONS:
The major accumulation of radioactivity occurred in glandular trichome cells, and the product remained stable throughout.
