Leiocarposide | CAS:71953-77-0 | Manufacturer ChemFaces

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

BMC Plant Biol.2018, 18(1):122

Eur J Pharmacol.2020, 889:173589.

Arch Toxicol.2024, 98(5):1415-1436.

Molecules.2019, 24(11):E2102

Asian J of Pharmaceutical&Clinical 2018, 11(2)

Pharmaceuticals (Basel).2024, 17(3):352.

Biomolecules.2024, 14(5):589.

Heliyon.2024, 10(11):e32352.

Microb Pathog.2019, 131:128-134

Int. J. of Food Properties2017, S108-S118

Pharmazie, 1989, 44(8):555-558.

Biotransformation of phenolglycosides leiocarposide and salicin.[Reference: WebLink]

Leiocarposide (1; 3-beta-D-glucopyranosyloxy-2-methoxy-6-hydroxy-benzoic acid -2'-beta-D-glucopyranosyloxybenzyl ester) is a phenolic glycoside from Solidago virgaurea L.
METHODS AND RESULTS:
After oral administration to rats it will be only poorly absorbed and mostly unchanged fecaly excreted. In the urine were found less than 10% as metabolites: leiocarpic acid (3; 3,6-dihydroxy-2-methoxy-benzoic acid, 2% of the administered dose), 3-conjugates (2%), salicylic acid (5; 0.5%), 5-conjugates (0.1%) and salicyluric acid (6; 0.5%). On the other hand salicin (2), structural part of 1, is good absorbed. In the urine were excreted 15% of the unchanged drug and the following metabolites: 0.1% saligenin (4), 30% 5, 5% 5-conjugates, 0.1% 6, 2% gentisic acid (7) and 0.1% 2,3-dihydroxy-benzoic acid (8).
CONCLUSIONS:
The different metabolic rates are explicable by the high stability of the ester bond of 1. It is hydrolyzed in artificial intestinal fluid only very slowly (t1/2 = 41.7 h).

Product Name	Leiocarposide
CAS No.:	71953-77-0
Catalog No.:	CFN70442
Molecular Formula:	C₂₇H₃₄O₁₆
Molecular Weight:	614.6 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Solidago virgaurea
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Price: