Product Name Hupehenine
CAS No.: 98243-57-3
Catalog No.: CFN90475
Molecular Formula: C27H45NO2
Molecular Weight: 415.65 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Cryst.
Source: The bulbus of Fritillaria thunbergii Miq.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $268/10mg
Hupehenine is a natural product from Fritillaria thunbergii Miq.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to:

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Arch Pharm Res.2014 Oct 18.
  • Sci Rep. 2017 Jun 12;
  • J Ethnopharmacol. 2017 Jan 20;
  • Molecules 2016, 21(6)2016 Jun 22;21(6).
  • Journal of Agricultural Science2015 Sep 15
  • Food and Bioprocess TechnologyJune 2017
  • Int. Conference on Med. Sci. and Bio.2017;
  • The Korea Society of Pharmacognosy.2014
  • International Journal of Mol. Med.2015 Mar 6.
  • J. of Food Composition & Analysis2017
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    Analysis of Hupehenine in the Total Alkaloids from Fritillaria hupehensis by HPLC-ELSD[Reference: WebLink]
    A reverse-phase high pressure liquid chromatography (HPLC) method with evaporative light scattering detection (ELSD) has been developed for the quantitative analysis of Hupehenine in the total alkaloids from Fritillaria hupehensis.
    Samples were analyzed on a reverse-phase column (Hypersil C-18) with a mobile phase of methanol:water:chloroform: triethylamine (85:15:1:0.6). The ELSD was set at the drift tube temperature of 68.3℃ and gas flow rate of 1.8 L/min. Hupehenine's retention time was 13.7 min with an asymmetry factor of 1.2. The validity of the method has been verified with linearity, limit of detection, accuracy and precision. The logarithmic linear curve was obtained from 8.936 to 134.04 μg/mL (r=0.9993). The detection limit (S/N>3) of Hupehenine was 1.79 μg/mL on the column. Intra-day RSD was 1.42% and inter-day RSD was 2.26% (3 days within a week). The average recovery of Hupehenine was 101.50%, and RSD was 1.62%.

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