Hispidanin B
Hispidanin B shows significant cytotoxicities against tumor cell lines SGC7901, SMMC7721, and K562, with IC50 values of 10.7, 9.8, and 13.7 uM, respectively.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Biomolecules.2021, 11(10):1537.
Separations2023, 10(4),255.
Nutr Res Pract.2020, 14(3):203-217.
Fitoterapia.2024, 106006.
Hum Exp Toxicol.2023, 42:9603271231171642.
Processes2023, 11(2), 385¡£
Eur J Ther.2023, 29(4):900-906.
Biochem Biophys Res Commun.2018, 505(4):1148-1153
Biochem Biophys Res Commun.2020, 530(1):4-9.
Acta Pharm Sin B.2024, 14(4):1772-1786.
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Org Lett. 2014 Jul 3;16(13):3552-5.
Hispidanins A-D: four new asymmetric dimeric diterpenoids from the rhizomes of Isodon hispida.[Pubmed:
24956015 ]
METHODS AND RESULTS:
Hispidanin A, Hispidanin B,Hispidanin C, Hispidanin D (1-4), four unprecedented asymmetric dimeric diterpenoids, were obtained from the rhizomes of Isodon hispida. Their structures were elucidated by extensive spectroscopic analysis (1D and 2D NMR, MS, UV, IR), as well as single-crystal X-ray diffraction analysis.
CONCLUSIONS:
Hispidanin B showed significant cytotoxicities against tumor cell lines SGC7901, SMMC7721, and K562, with IC50 values of 10.7, 9.8, and 13.7 μM, respectively.
