Diosbulbin L
Diosbulbin L is a natural product from Dioscorea bulbifera.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytochemistry. 2010 Jul;71(10):1174-80.
Norclerodane diterpenoids from rhizomes of Dioscorea bulbifera.[Pubmed:
20452632 ]
METHODS AND RESULTS:
Three norclerodane diterpenoids, diosbulbin K, Diosbulbin L, diosbulbin M, and one analogous enolglycoside, diosbulbinoside G, together with four norclerodane diterpenoids, diosbulbins B, E, F and G, were isolated from rhizomes of Dioscorea bulbifera. Their structures were established by spectroscopic and chemical methods, including 1H and 13C NMR, NOESY, HSQC, HMBC, and HRMS analyses. The relative configurations of diosbulbin K and Diosbulbin L, and diosbulbin F were confirmed by X-ray crystallographic diffraction analysis, and the absolute stereochemistry of diosbulbin K was determined by a modified Mosher's method.
The 13C NMR spectroscopic data for diosbulbins E, F and G were also measured for the first time.
CONCLUSIONS:
The compounds did not show significant cytotoxic and anti-bacterial activities.
