Dihydrooroxylin A
Dihydrooroxylin A has significant antifeeding activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytochemistry. 2004 Jul;65(14):2173-6.
Insect antifeedant compounds from Nothofagus dombeyi and N. pumilio.[Pubmed:
15279992]
METHODS AND RESULTS:
A bioassay-guided purification of the extracts of Nothofagus dombeyi and N. pumilio leaves yielded several triterpenes and flavonoids including 2-O-acetylmaslinic acid, 3-O-acetyl 20,24,25-trihydroxydammarane, and 3,20,24,25-tetrahydroxydammarane as new natural products. All the isolated compounds were assessed for antifeeding activity against the 5th instar larvae of Ctenopsteustis obliquana.
CONCLUSIONS:
12-Hydroxyoleanolic lactone and pectolinarigenin from N. dombeyi and Dihydrooroxylin A from N. pumilio, showed significant antifeeding activity.
Biol Pharm Bull. 1998 Dec;21(12):1251-7.
Characteristics of delayed excretion of flavonoids in human urine after administration of Shosaiko-to, a herbal medicine.[Pubmed:
9881633 ]
METHODS AND RESULTS:
Two flavanones, S-dihydrowogonin and S-Dihydrooroxylin A, were identified as the metabolites of wogonin and oroxylin A, respectively. Excretion rate-time curves of the flavonoids were divided into three types of structure-dependent absorption, i.e. (1) the fast absorption of herbal-origin aglycons, (2) the moderately-delayed absorption of aglycons derived from herbal glycosides, and (3) markedly-delayed absorption after the molecular transformation of herbal compounds. Individual excretion profiles seemed to depend on microflora activities.
CONCLUSIONS:
Two types of flavanones, S-dihydrowogonin and S-Dihydrooroxylin A, were found in a half of the volunteers, suggesting there might be two kinds of volunteers, namely, rapid and poor metabolizers of flavonoids.
