Daidzein dimethyl ether
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
JPC-Journal of Planar Chromatography 2017, 30(4)
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J Korean Soc Food Sci Nutr2023, 52(12):1248-1255
Processes2023, 11(2), 385ĄŁ
J Cell Mol Med.2023, jcmm.18071.
Plos One.2019, 15(2):e0220084
Appl. Sci.2020, 10(20), 7323.
Nat Chem Biol.2018, 14(8):760-763
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Proceedings of the Indian Academy of Sciences - Section A, 1951, 33(5):257-263.
Synthetic experiments in the benzopyrone series.[Reference:
WebLink]
The study of daidzein derivatives provides further support to the conclusions already arrived at regarding the special features of partial methylation and demethylation in the isoflavone series.
METHODS AND RESULTS:
Partial methylation of daidzein gives a good yield of the 7-monomethyl ether (isoformononetin) and the formation of the isomeric formononetin could not be detected. The same 7-methyl ether is obtained most conveniently by the demethylation of Daidzein dimethyl ether with hydrobromic acid and hydriodic acid. 5:7-Dihydroxy and di-methoxy isoflavones have also been examined with a view to compare them with corresponding flavones.
CONCLUSIONS:
7-Methoxy-5-hydroxy isoflavone is obtained most readily by partial demethylation of dimethoxy isoflavone with hydriodic acid whereas chrysin dimethyl ether yields mostly chrysin under these conditions.
