Cytisine Hydrochloride

Cytisine Hydrochloride
Product Name Cytisine Hydrochloride
CAS No.: 6047-01-4
Catalog No.: CFN80438
Molecular Formula: C11H14N2O.HCl
Molecular Weight: 226.70 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Genista tinctoria L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Cytisine hydrochloride has toxicity.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Int J Nanomedicine.2024, 19:1683-1697.
  • Biomed Pharmacother.2022, 156:113929.
  • Food Chem.2024, 452:139555.
  • Phytochem Anal.2022, doi: 10.1002
  • Foods.2024, 13(11):1739.
  • J Adv Res.2021, 35:245-257.
  • Int J Mol Sci.2023, 24(8):7442.
  • Sci Rep.2015, 5:13194
  • J Food Biochem.2020, 44(6):e13198.
  • Phytother Res.2020, 34(4):788-795.
  • 7-Epitaxol

    Catalog No: CFN90371
    CAS No: 105454-04-4
    Price: $60/20mg
    Isoescin IA

    Catalog No: CFN90932
    CAS No: 219944-39-5
    Price: $238/20mg
    Aerugidiol

    Catalog No: CFN92621
    CAS No: 116425-35-5
    Price: $318/10mg
    Aristolochic acid A

    Catalog No: CFN99505
    CAS No: 313-67-7
    Price: $80/20mg
    Alisol B 23-acetate

    Catalog No: CFN99753
    CAS No: 26575-95-1
    Price: $50/20mg
    Br J Pharmacol. 1969 Jan;35(1):161-74.
    Some studies on cytisine and its methylated derivatives.[Pubmed: 4387392]

    METHODS AND RESULTS:
    1. In mice Cytisine Hydrochloride is less toxic intravenously than nicotine hydrogen tartrate, but more toxic by intraperitoneal or oral administration. Compared with cytisine, caulophylline hydrogen iodide is one-fifth to one-tenth as toxic and caulophylline methiodide is less than one-thirtieth as toxic.2. The surprising low oral toxicity of cytisine and nicotine may be ascribed to the method of administration; if the drug is placed directly in the stomach there is no possibility of absorption through buccal mucous membranes.3. The peripheral effects of nicotine, cytisine and caulophylline are similar, though on some preparations those of nicotine last longer. In most tests cytisine is active in doses from a quarter to three-quarters of those of nicotine, caulophylline in doses from 10 to 20 times those of cytisine. Caulophylline methiodide is virtually inactive.4. Cytisine and caulophylline may differ from nicotine in their central effects.5. Cytisine and caulophylline are active as the cations. The pKa of cytisine is 7.92 and that of caulophylline is 7.04; the difference accounts, in part, for the weaker activity of caulophylline. The caulophylline ion is generally one-sixth to one-third as active as the cytisine ion.6. The introduction of the second methyl group to form the quaternary salt does not appear to cause a dramatic change in the conformation of the molecule.
    CONCLUSIONS:
    Caulophylline methiodide appears to be feebly active because it has feeble affinity.
    Suchilactone

    Catalog No: CFN95010
    CAS No: 50816-74-5
    Price: $338/5mg
    Poricoic acid B

    Catalog No: CFN95050
    CAS No: 137551-39-4
    Price: $318/20mg
    24-Hydroxymomordicine III

    Catalog No: CFN95169
    CAS No: N/A
    Price: $318/5mg
    Neochlorogenic acid methyl ester

    Catalog No: CFN95190
    CAS No: 123410-65-1
    Price: $198/5mg
    (-)-Cadin-4,10(15)-dien-11-oic acid

    Catalog No: CFN95246
    CAS No: 1124353-23-6
    Price: $318/5mg
    Acacetin 7-[rhamnosyl-(1->2)-galacturonide]

    Catalog No: CFN95358
    CAS No: 38722-95-1
    Price: $318/10mg
    4'-Hydroxy-5,7,3'-trimethoxyflavone

    Catalog No: CFN95398
    CAS No: 1239-68-5
    Price: $318/5mg
    Quercetin-3-O-[alpha-L-rhamnose-(1->2)-beta-D-glucopyranosyl]-5-O-beta-D-glucopyranoside

    Catalog No: CFN95506
    CAS No: 1309795-36-5
    Price: $318/5mg
    Methyl ganoderate F

    Catalog No: CFN95584
    CAS No: 98665-08-8
    Price: $368/5mg
    4-Keto-laurifoline

    Catalog No: CFN95594
    CAS No: N/A
    Price: $318/10mg