Cycloolivil

Cycloolivil
Product Name Cycloolivil
CAS No.: 3064-05-9
Catalog No.: CFN96185
Molecular Formula: C20H24O7
Molecular Weight: 376.4 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Targets: Calcium Channel
Source: The herbs of Maytenus hookeri Loes.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $268/5mg
(+)-Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Molecules.2020, 25(18),4089.
  • Int J Mol Sci.2019, 20(3):E651
  • Biochem Biophys Res Commun.2020, 527(4):889-895.
  • Dental Journal2024, 57(4): 254-258
  • Theranostics.2023, 13(9):3103-3116.
  • Current Topics in Nutraceutical Research2021, 19(1),p90-105.
  • Phytochem Anal.2016, 27(5):296-303
  • Int J Mol Sci.2022, 23(23):14545.
  • Journal of Food and Drug Analysis2023, 31(3), 9.
  • Front Microbiol.2022, 13:835463.
  • Nudiposide

    Catalog No: CFN89146
    CAS No: 62058-46-2
    Price: $318/5mg
    Isotaxiresinol 9,9'-acetonide

    Catalog No: CFN97774
    CAS No: 252333-72-5
    Price: Inquiry(manager@chemfaces.com)
    Cycloolivil

    Catalog No: CFN96185
    CAS No: 3064-05-9
    Price: $268/5mg
    Isolariciresinol

    Catalog No: CFN98915
    CAS No: 548-29-8
    Price: $218/5mg
    9,9'-O-Isopropyllidene-isolariciresinol

    Catalog No: CFN98276
    CAS No: 252333-71-4
    Price: Inquiry(manager@chemfaces.com)
    Schizandriside

    Catalog No: CFN96693
    CAS No: 71222-06-5
    Price: Inquiry(manager@chemfaces.com)
    (-)-Isolariciresinol 9'-O-glucoside

    Catalog No: CFN89431
    CAS No: 143236-04-8
    Price: $318/5mg
    Vitexdoin A

    Catalog No: CFN96194
    CAS No: 1186021-77-1
    Price: Inquiry(manager@chemfaces.com)
    7,8,9,9-Tetradehydroisolariciresinol

    Catalog No: CFN99605
    CAS No: 145918-59-8
    Price: Inquiry(manager@chemfaces.com)
    Vitedoin A

    Catalog No: CFN96448
    CAS No: 819861-40-0
    Price: Inquiry(manager@chemfaces.com)
    Blood Cell. Mol. Dis., 2009, 42(3):279-85.
    Olive tree wood phenolic compounds with human platelet antiaggregant properties.[Pubmed: 19195914]
    Oleuropein and (+)-Cycloolivil are natural polyphenolic compounds with a significant radical scavenging activity present in olive tree. We have investigated the antiaggregant effects of oleuropein and (+)-Cycloolivil isolated from an ethyl acetate extract of olive tree wood.
    METHODS AND RESULTS:
    Oleuropein and (+)-Cycloolivil reduced the ability of thrombin to stimulate platelet aggregation. Both compounds reduced thrombin-evoked Ca(2+) release and entry to a similar extent to hydroxytyrosol. This effect was greater in platelets from patients with type 2 diabetes mellitus than in controls. Thrombin-, thapsigargin- and 2,5-di-(tert-butyl)-1,4-hydroquinone (TBHQ)-evoked protein tyrosine phosphorylation, which is involved in Ca(2+) signalling and platelet aggregation, is inhibited by oleuropein and (+)-Cycloolivil. oleuropein and (+)-Cycloolivil are natural oxygen radical scavengers that reduce thrombin-induced protein tyrosine phosphorylation, Ca(2+) signalling and platelet aggregation.
    CONCLUSIONS:
    These observations suggest that oleuropein and (+)-Cycloolivil may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies.
    Polygalin C

    Catalog No: CFN95118
    CAS No: 934768-05-5
    Price: $288/5mg
    Rhamnocitrin 3-glucoside

    Catalog No: CFN95134
    CAS No: 41545-37-3
    Price: $318/10mg
    Pueroside B

    Catalog No: CFN95141
    CAS No: 100692-54-4
    Price: $288/10mg
    Momordicoside X

    Catalog No: CFN95170
    CAS No: 1333321-50-8
    Price: $368/5mg
    N-Methylcorydalmine

    Catalog No: CFN95204
    CAS No: 81010-29-9
    Price: $398/5mg
    N1,N5,N10-(Z)-tri-p-coumaroylspermidine

    Catalog No: CFN95253
    CAS No: 131086-78-7
    Price: $238/5mg
    11-Oxomogroside IIA2

    Catalog No: CFN95305
    CAS No: 2170761-37-0
    Price: $368/5mg
    10-O-trans-p-Feruloylscandoside

    Catalog No: CFN95392
    CAS No: 1428268-72-7
    Price: $318/10mg
    5-Demethylsinensetin

    Catalog No: CFN95415
    CAS No: 21763-80-4
    Price: $318/10mg
    Cannabisin P

    Catalog No: CFN95456
    CAS No: 2756983-19-2
    Price: $318/5mg