Caesalmin E

Caesalmin E
Product Name Caesalmin E
CAS No.: 204185-91-1
Catalog No.: CFN96944
Molecular Formula: C26H36O9
Molecular Weight: 492.56 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Targets: Antifection
Source: The seed kernels of Caesalpinia crista.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Caesalmin E shows anti-Para3 virus activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    J Nat Prod. 2001 Oct;64(10):1266-72.
    New antiviral cassane furanoditerpenes from Caesalpinia minax.[Pubmed: 11678648]
    A bioassay-guided study led to the isolation of five new cassane furanoditerpenes, designated as caesalmin C (1), caesalmin D (2), Caesalmin E (3), caesalmin F (4), and caesalmin G (5), along with stigmasterol (6) from the seeds of Caesalpinia minax.
    METHODS AND RESULTS:
    The (1)H and (13)C NMR spectra were completely assigned by using a combination of 2D NMR analyses. The structures of all five furanoditerpenes were confirmed by X-ray analyses. The structure of 6 was verified by X-ray analysis for the first time.
    CONCLUSIONS:
    The bioassay results showed that the anti-Para3 virus activity of tetracyclic furanoditerpenoids 1-4 is more potent than that of the furanoditerpenoid lactone 5, which is in turn better than 6. As the major components of the plant possess significant potent activity, it may be feasible to develop new antiviral agents from this source.
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    METHODS AND RESULTS:
    From the CH(2)Cl(2) extract of seed kernels of Caesalpinia crista from Myanmar, five new cassane-type diterpenes, caesalpinins MA-ME (1-5), and three new norcassane-type diterpenes, norcaesalpinins MA-MC (6-8), have been isolated, together with 12 known cassane-type diterpenes, 14(17)-dehydrocaesalmin F, caesaldekarin e, caesalmin B, caesalmin C, Caesalmin E, 2-acetoxy-3-deacetoxycaesaldekarin e, 2-acetoxycaesaldekarin e, caesalpinin C, 7-acetoxybonducellpin C, caesalpinin E, norcaesalpinin B, and 6-acetoxy-3-deacetoxycaesaldekarin e.
    CONCLUSIONS:
    The structures of the isolated compounds were elucidated by analysis of their spectroscopic data.
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