5-Methoxyisolariciresinol
(+)-5-Methoxyisolariciresinol displays significant antioxidant activities, with the IC(50) value in the range of ca. 42 to 49 microg/ml.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Nat Prod.2022, 85(5):1351-1362.
Front Pharmacol.2018, 9:236
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J Agric Food Chem.2024, 72(42):23183-23195
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Chem Biodivers. 2006 Feb;3(2):224-30.
New antioxidant phenolic glycosides from Walsura yunnanensis.[Pubmed:
17193261 ]
METHODS AND RESULTS:
Four new polyphenolic glycosides (1-4) were isolated from the BuOH extract of the bark of Walsura yunnanenis C. Y. Wu.
These compounds comprise two lignans, i.e., the 9-O-alpha-L-arabinopyranosides 1 and 2 of (-)-isolariciresinol and of (+)-5-Methoxyisolariciresinol, respectively, and the two phenolic glycosides 3,4,5-trimethoxyphenyl 2-O-(alpha-L-fucopyranosyl)-beta-D-glucopyranoside (3) and 3,5-dihydroxyphenyl 6-O-(4-hydroxy-3,5-dimethoxybenzoyl)-beta-D-glucopyranoside (walsuraside; 4). In addition, three known compounds, 3,4,5-trimethoxyphenyl beta-D-glucopyranoside, asperglaucide, and butyl alpha-D-fructofuranoside were identified. Their structures were elucidated spectroscopically and by chemical transformation (hydrolysis).
CONCLUSIONS:
The new compounds 1, 2, and 4 displayed significant antioxidant activities, with IC(50) values in the range of ca. 42 to 49 microg/ml.
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