5-Geranoxy-7-methoxycoumarin
5-Geranoxy-7-methoxycoumarin shows antifungal activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Journal of Agricultural and Food Chemistry, 1992, 40(7):1217-1221.
Preformed and induced antifungal materials of citrus fruits in relation to the enhancement of decay resistance by heat and ultraviolet treatments.[Reference:
WebLink]
Two mechanisms of the resistance of citrus fruits against pathogens-preformed and induced antifungal materials-were investigated.
METHODS AND RESULTS:
Flavedo tissue of lemon contains the following preformed antifungal materials: citral, limettin, 5-Geranoxy-7-methoxycoumarin, and isopimpinellin, which act as the first line of defense against pathogens. Exogenous application of citral to Penicillium-inoculated lemon fruit prevented development of decay. Being subjected to fungal challenge and/or abiotic stress, citrus fruits are elicited to produce the phytoalexin scoparone, considered as another line of fruit defense. According to median effective dose (ED50) of the inhibition of germ-tube elongation or percent germination, scoparone had higher fungitoxicity against Penicillium digitatum Sacc. than the preformed antifungal materials. Different citrus species (lemon, orange, grapefruit, lime, kumquat) varied in their capacities to produce scoparone responding to the combined Penicillium inoculation and heat treatment or to UV illumination. UV illumination of lemon fruit reduced its susceptibility to P. digitatum.
CONCLUSIONS:
Expression of this effect was directly related to the level of scoparone in illuminated fruit. UV light and citral application were visibly injurious to the flavedo tissues in high dose.
Phytochemistry, 1967, 6(4):585–596.
Psoralens and substituted coumarins from expressed oil of lime.[Reference:
WebLink]
METHODS AND RESULTS:
Chromatography on silica gel columns isolated ten crystalline solids from expressed West Indian lime (Citrus aurantifolia) oil. Of the eight compounds identified, three were those previously reported by Caldwell and Jones, i.e. 5-Geranoxy-7-methoxycoumarin, 5,7-dimethoxycoumarin and 5,8-dimethoxypsoralen (isopimpinellin). The following new compounds were identified: 5-geranoxypsoralen (bergamottin), 5-γ,γ-dimethylallyloxypsoralen (isoimperatorin), 8-geranoxypsoralen, 8-γ,γ-dimethylallyloxypsoralen (imperatorin); and 5-methoxy-8-γ,γ-dimethylallyloxypsoralen (phellopterin).
CONCLUSIONS:
Two compounds were tentatively identified as 5-geranoxy-8-methoxypsoralen and oxypeucedanin hydrate.
