3,4-Dimethoxyacetophenone
3,4-Dimethoxyacetophenone can induce negative phototaxis in Chlamydomonas.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Chemical Biology & Drug Design, 2010, 75(3):333-337.
Select acetophenones modulate flagellar motility in chlamydomonas.[Pubmed:
20659114]
METHODS AND RESULTS:
Acetophenones were screened for activity against positive phototaxis of Chlamydomonas cells, a process that requires co-ordinated flagellar motility.
The structure-activity relationships of a series of acetophenones are reported, including acetophenones that affect flagellar motility and cell viability.
CONCLUSIONS:
Notably, 4-methoxyacetophenone, 3,4-Dimethoxyacetophenone, and 4-hydroxyacetophenone induced negative phototaxis in Chlamydomonas, suggesting interference with activity of flagellar proteins and control of flagellar dominance.
