2-O-Methylanigorufone

2-O-Methylanigorufone
Product Name 2-O-Methylanigorufone
CAS No.: 56252-05-2
Catalog No.: CFN96873
Molecular Formula: C20H14O2
Molecular Weight: 286.33 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The whole plants of Monochoria vaginalis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
2-O-Methylanigorufone is a natural product from Monochoria vaginalis.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    The aquatic plant Monochoria vaginalis var. plantaginea (Roxb.) Solms (Pontederiaceae) is a traditional herbal medicine, and widely distributed in Asian countries including Korea, China, Japan, India, and Malaysia. The whole plant is considered as a functional food and has also been used for treatment of dysentery, enteritis, acute tonsillitis, gum abscesses, erysipelas, boils. Juice of the leaves is taken for coughs and that of the root for stomach and liver complaints, asthma and toothache.
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    In our continuing studies to find bioactive compounds from natural products, several structures were isolated from the whole plant of Monochoria vaginalis var. plantaginea. Among five fractions of the MeOH extract, the n-hexane fraction exhibited comparatively higher antioxidative and cytotoxic activities than the other fractions. The CH2Cl2 and BuOH fractions also showed strong antioxidative activity. Ten compounds were isolated from the n-hexane and CH2Cl2 fractions, and their structures were identified as cholest-4-en-3,6-dione, stigmast-4-ene-3,6-dione, methoxyanigorufone(2-O-Methylanigorufone), (10Z)-1-(2,6-dihydroxyphenyl)octadec-10-en-1-one, 1-(4-methoxyphenyl)-7-phenyl-(6E)-6-hepten-3-one, (+)-dehydrovomifoliol, 4-hydroxyphenylacetonitrile, (6R,9S)-vomifoliol, (6S,9S)-vomifoliol, (3S,5R,6R,7E,9R)-5,6-epoxy-3,9-dihydroxy-7-megastigmene by comparison of their spectral data with literature values. Cytotoxic and antioxidative activities for solvent fractions and isolated compounds were evaluated using SRB (sulforhodamin B) assay against human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT15), and ORAC (oxygen radical absorbance capacity) assay, respectively.
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    METHODS AND RESULTS:
    A new natural product of the phenylphenalenone type, 3-hydroxy-4-phenyl-1H,3H-benzo[de]isochromen-1-one, and two known natural products, methoxyanigorufone(2-O-Methylanigorufone) and isoanigorufone, were isolated and identified by NMR spectroscopy and mass spectrometry. Additionally, by HPLC analysis, three condensed dimeric phenylphenalenones, namely anigorootin, 4′-hydroxyanigorootin, 4',4''-Dihydroxyanigorootin, were identified.
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