1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane
1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane is a natural product from Ligularia fischeri.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Cell Rep.2022, 39(1):110643.
Phytother Res.2018, 32(12):2551-2559
Foods.2021, 10(6):1378.
Food Sci Biotechnol.2024, 33(15):3629-3637.
Int J Mol Sci.2024, 25(18):10219.
Sci Rep. 2017, 12953(7)
Int J Mol Sci.2024, 25(5):2799.
Sci Rep. 2018, 1-9
Separations2023, 10(4),255.
Sichuan Agricultural University2023, 4630743.
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J Nat Prod. 2010 Feb 26;73(2):143-6.
A pair of epimeric spirosesquiterpenes from the roots of Ligularia fischeri.[Pubmed:
20104879 ]
METHODS AND RESULTS:
Two new highly oxygenated spirosesquiterpene lactones, ligulactones A (1) and B (2), and one known sesquiterpenoid, 1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane (3), were isolated from the roots of Ligularia fischeri. Their structures and relative configurations were elucidated by 1D and 2D NMR and MS data and by comparison of their NMR data with those of related compounds. Single-crystal X-ray diffraction analyses confirmed their structures.
CONCLUSIONS:
Compounds 1 and 2 are C-7 epimers. A possible biosynthetic process for their formation is proposed. Structure 3 was proposed as the likely parent compound for the two new epimeric sesquiterpenoids.
