16-Nor-15-oxodehydroabietic acid
16-Nor-15-oxodehydroabietic acid is a natural product from Pinus massoniana.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Metabolites2023, 13(1), 3.
Sci Rep.2019, 9(1):6429
Biochem Systematics and Ecology2017, 11-18
Molecules.2023, 28(17):6315.
PLoS One.2018, 13(3):e0193386
South African Journal of Botany2024, 168:209-220.
BioRxiv-The Preprint server for biology2023, 586957.
Front Pharmacol.2019, 10:1025
Anticancer Res.2020, 40(10):5529-5538.
Evid Based Complement Alternat Med.2017, 2017:6360836
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Phytochemistry, 1997 , 46 (6) :1051-1057.
Abietane diterpene acids and other constituents from the leaves of Larix kaempferi[Reference:
WebLink]
METHODS AND RESULTS:
The new diterpene acids were isolated from the leaves of Larix kaempferi, together with two known sesquiterpenes, (−)-α-cadinol and oplopanone, and 10 known diterpenes, larixol, dehydroabietinol, 7-oxo-dehydroabietinol, 7-oxodehydroabietic acid, 9α,13α-epidioxyabiet-8(14)-en-18-oic acid, 9β,13β-epidioxyabiet-8(14)-en-18-oic acid, dehydroabietic acid, 7α-hydroxydehydroabietic acid, 8α,9α,13α,14α-diepoxyabietan-18-oic acid and 15-hydroxydehydroabetic acid.
CONCLUSIONS:
The new acids and their methyl esters were characterized as methyl abieta-8,11,13,15-tetraen-18-oic acid, methyl 16-Nor-15-oxodehydroabietic acid and methyl 12,15-dihydroxydehydroabietic acid, on the basis of chemical and spectroscopic evidence.
