1-Hydroxybaccatin I

1-Hydroxybaccatin I
Product Name 1-Hydroxybaccatin I
CAS No.: 30244-37-2
Catalog No.: CFN98378
Molecular Formula: C32H44O14
Molecular Weight: 652.7 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Cryst.
Source: The barks of Taxus chinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
1beta-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Pharmaceutics.2020, 12(9):845.
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • Process Biochemistry2019, 87:213-220
  • Process Biochemistry2019, 85:106-115
  • J Ethnopharmacol.2024, 318:116863.
  • Molecules.2023, 28(2):727.
  • Food Chem.2020, 332:127412
  • J Ginseng Res.2023, 47(4):593-603.
  • JMicrobiol Biotech Food Sci2021, e4289.
  • Metabolites2022, 12(6),507.
  • 2,7-Dideacetoxytaxinine J

    Catalog No: CFN96979
    CAS No: 115810-14-5
    Price: Inquiry(manager@chemfaces.com)
    9-Deacetyltaxinine E

    Catalog No: CFN96923
    CAS No: 284672-78-2
    Price: Inquiry(manager@chemfaces.com)
    Taxinine

    Catalog No: CFN96636
    CAS No: 3835-52-7
    Price: Inquiry(manager@chemfaces.com)
    Taxinine J

    Catalog No: CFN96635
    CAS No: 18457-46-0
    Price: Inquiry(manager@chemfaces.com)
    Taxinine M

    Catalog No: CFN96634
    CAS No: 135730-55-1
    Price: Inquiry(manager@chemfaces.com)
    Decinnamoyltaxagifine

    Catalog No: CFN89028
    CAS No: 130394-69-3
    Price: Inquiry(manager@chemfaces.com)
    Taxumairol R

    Catalog No: CFN96631
    CAS No: 244167-04-2
    Price: Inquiry(manager@chemfaces.com)
    Tasumatrol L

    Catalog No: CFN96647
    CAS No: 847835-17-0
    Price: Inquiry(manager@chemfaces.com)
    Taxagifine

    Catalog No: CFN96641
    CAS No: 81489-69-2
    Price: Inquiry(manager@chemfaces.com)
    Taxezopidine L

    Catalog No: CFN96638
    CAS No: 219749-76-5
    Price: Inquiry(manager@chemfaces.com)
    J Nat Med. 2013 Jul;67(3):512-8.
    Development of an indirect competitive enzyme-linked immunosorbent assay (icELISA) using highly specific monoclonal antibody against paclitaxel.[Pubmed: 23007175]
    Paclitaxel, the major active component of the yew tree, is used as an important anti-cancer agent.
    METHODS AND RESULTS:
    To obtain the monoclonal antibody (MAb) against paclitaxel for paclitaxel determination using immunoassay, 7-xylosyltaxol was conjugated to the carrier protein bovine serum albumin (BSA) to construct the immunogen, and the ratio of hapten in XylTax-BSA conjugate was determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. After immunization of mice with this conjugate, hybridomas secreting MAbs against paclitaxel were obtained by fusing the splenocytes with the mouse myeloma cell line SP2/0. After hybridoma screening, the anti-paclitaxel MAb 3A3 was obtained, which showed a relatively high specificity to paclitaxel (cross-reactivities against other naturally occurred taxanes: 7-xylosyltaxol, 31.8%; cephalomannine, 6.17%; baccatin III, 10-deacetyl-baccatin III, 1-Hydroxybaccatin I, 13-acetyl-9-dihydrobaccatin III and 1-acetoxyl-5-deacetyl-baccatin I, <0.11%). Using the MAb 3A3, we established an indirect competitive enzyme-linked immunosorbent assay (icELISA) for paclitaxel determination with a detection range of 0.098-312.5 μg ml(-1). Determination of paclitaxel contents in various yew tree samples with this icELISA resulted in recovery rates ranging from 92 to 94.8%, and intra- and inter-assay variations of 3.6 and 4.7%, respectively.
    CONCLUSIONS:
    This icELISA provides a valuable method of paclitaxel determination for various purposes.
    J Ethnopharmacol. 2003 Dec;89(2-3):265-70.
    Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L.[Pubmed: 14611890]

    METHODS AND RESULTS:
    Four taxoids (taxusin, baccatin VI, baccatin III and 1beta-hydroxybaccatin I(1-Hydroxybaccatin I)) and five lignans (lariciresinol, taxiresinol, 3'-demethylisolariciresinol-9'-hydroxyisopropylether, isolariciresinol and 3-demethylisolariciresinol) were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through chromatographic techniques. In vivo anti-inflammatory and antinociceptive activity of these compounds were investigated.
    CONCLUSIONS:
    All the compounds were shown to possess significant antinociceptive activity against p-benzoquinone-induced abdominal contractions, while only lignan derivatives significantly inhibited carrageenan-induced hind paw edema in mice.
    Caohuoside E

    Catalog No: CFN95016
    CAS No: 174286-23-8
    Price: $318/5mg
    Specioside B

    Catalog No: CFN95165
    CAS No: 126589-95-5
    Price: $368/5mg
    N-Methylcorydalmine

    Catalog No: CFN95204
    CAS No: 81010-29-9
    Price: $398/5mg
    Trachelogenin 4'-O-beta-gentiobioside

    Catalog No: CFN95235
    CAS No: 106647-13-6
    Price: $218/10mg
    9-Hydroxy-O-senecioyl-8,9-dihydrooroselol

    Catalog No: CFN95274
    CAS No: 31456-63-0
    Price: $318/5mg
    Secotubeimoside I

    Catalog No: CFN95347
    CAS No: 106235-32-9
    Price: $318/10mg
    New compound 11

    Catalog No: CFN95351
    CAS No: N/A
    Price: $318/10mg
    New compound 14

    Catalog No: CFN95381
    CAS No: N/A
    Price: $413/5mg
    10-Deacetylcephalomannine

    Catalog No: CFN95519
    CAS No: 76429-85-1
    Price: $318/10mg
    11-Keto-ganoderic acid DM

    Catalog No: CFN95593
    CAS No: N/A
    Price: $413/5mg