Inhibitors

Glycyrrhisoflavone
Catalog No: CFN90817

Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase. Glycybenzofuran shows significant protein tyrosine phosphatase-1B (PTP1B) inhibitory activity in vitro with the IC50 value of 25.5 microM. Glycyrrhisoflavone has anti-inflammatory effects, it has significant inhibitory effects against NO production on LPS-induced RAW 264.7 cell model.

Mauritianin
Catalog No: CFN90819

Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors. Mauritianin has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL.

Alpha-pinene
Catalog No: CFN93285

Alpha-pinene inhibits the nuclear translocation of NF-kappa B induced by LPS in THP-1 cells, and this effect is partly due to the upregulation of I kappa B alpha expression. Alpha-pinene inhibits early root growth and causes oxidative damage in root tissue through enhanced generation of ROS, as indicated by increased lipid peroxidation, disruption of membrane integrity and elevated antioxidant enzyme levels.

Ethyl 4-hydroxyphenylacetate
Catalog No: CFN93004

Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A.

Cassiaside
Catalog No: CFN90826

Cassiaside has significant hepato-protective effects against galactosamine damage, which is higher than that of silybin from Silybum marianum. Cassiaside demonstrates significant antimutagenic, and 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging effects. Cassiaside and emodi show mixed-type inhibition against β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1).