Cytotoxic

1alpha-Hydroxytorilin
Catalog No: CFN96357

1alpha-Hydroxytorilin exhibits cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.

Glutinol acetate
Catalog No: CFN96385

Glutinol acetate shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17.9microM; it also has anti-inflammatory effect, exhibits moderate inhibitory activity of TNF-alpha secretion in the lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cell line.

Yadanziolide B
Catalog No: CFN96427

Yadanziolide B exhibits cytotoxic activities with IC50 values of 3.00-5.81 uM.

Vitexolide D
Catalog No: CFN96446

Vitexolide D shows moderate antibacterial activity against a panel of 46 Gram-positive strains. It also shows cytotoxic activities against the HCT-116 cancer cell line and human fetal lung fibroblast MRC5 cell line (1 < IC50s < 10 uM).

Viroallosecurinine
Catalog No: CFN96450

Virosecurinine and viroallosecurinine were isolated as two cytotoxic alkaloids from the leaves of Securinega virosa. Viroallosecurinine exhibits a MIC of 0.48 micrograms/ml for Pseudomonas aeruginosa and Staphylococcus aureus.