Antifungal

Palmatine hydrochloride
Catalog No: CFN99124

Palmatine hydrochloride is a hydrochloride salt of palmatine which is a protoberberine alkaloid, it can induce remarkable cell apoptosis, has potential in photodynamic therapy on colon adenocarcinoma. Palmatine hydrochloride has anti-C. albicans effect, it mixes with berberine hydrochloride elicit antifungal activities, it also can reduce blood sugar and oxidative stress in STZ induced diabetic rats.

3,4-Dihydroxybenzaldehyde
Catalog No: CFN99450

3,4-Dihydroxybenzaldehyde, a potent tyrosinase inhibitor, has antifungal activity, it can inhibit oxidative DNA damage and apoptosis via its antioxidant activity. It inhibits the phosphotransferase activity of CKII with IC(50) of about 783 microM, it may function by inhibiting oncogenic disease, at least in part, through the inhibition of CKII activity. It inhibits the H2O2-induced apoptosis of granulosa cells, promotes estradiol secretion in granulosa cells and enhanced the mRNA expression levels of steroidogenic factor 1, a promoter of key steroidogenic enzymes.

Isoliquiritin
Catalog No: CFN99155

Isoliquiritin has significant antidepressant-like, antifungal and anti-cancer activities. It induces apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells and inhibit the p53-dependent pathway and showed crosstalk between Akt activities.

Eugenol
Catalog No: CFN99175

Eugenol is an essential oil found in cloves with herbicide,sedative,analgesic,antibacterial,anthelmintic,anti-inflammatory, cancer chemopreventive and antioxidant activities. Eugenol is shown to inhibit lipid peroxidation, the mRNA expression of COX-2, but not COX-1 and inhibit the GABAA current in trigeminal ganglion neurons. It could be developed as therapeutic agent against diseases with excessive osteoclast activity.

Macrocarpal C
Catalog No: CFN99469

Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifungal action of macrocarpal C was associated with increases of membrane permeability, intracellular ROS and DNA fragmentation.