Antifungal

Isodiospyrin
Catalog No: CFN98019

Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. Isodiospyrin has antibacterial activity, the minimum inhibitory concentrations (MICs) against Gram-positive bacteria ranged from 0.78 to 50 microg/mL; it shows high antifungal activity against P. obscurans at 30uM with 81.4% growth inhibition, and moderate activity against P. viticola (36.6%).

9,17-Octadecadiene-12,14-diyne-1,11,16-triol
Catalog No: CFN98061

(+)-9(Z),17-Octadecadiene-12,14-diyne-1,11,16-triol shows antibacterial activity against Bacillus subtilis and Pseudomonas fluorescens, antifungal activity against Cladosporium cucumerinum, moiluscicidal activity against Biomphalaria glabrata at low concentrations, and in addition it possesses haemolytic activity.

Shoreic acid
Catalog No: CFN98077

Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albicans and T. mentagrophytes with AI of 0.2 and 0.3, respectively. Shoreic acid shows activity against Mycobacterium tuberculosis. Shoreic acid also has antiviral activity against Herpes simplex virus types I and II in vitro.

Arctiin
Catalog No: CFN99991

Arctiin(NSC 315527), a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. Arctiin has been reported to have preventing obesity, antibacterial, antiviral, anti-inflammatory, and anti-oxidant effects in vitro. Arctiin inhibits adipogenesis in 3T3-L1 adipocytes through the inhibition of PPARγ and C/EBPα and the activation of AMPK signaling pathways. Arctiin also has a protective effect on ROS-induced cell dysfunction in HHDPCs and may therefore be useful for alopecia prevention and treatment strategies.

Pinosylvin
Catalog No: CFN98203

Pinosylvin is likely to act as a pro-angiogenic factor, it has anti-inflammatory activity, it may be utilized as a phytotherapic agent for the prevention of cardiovascular inflammatory diseases. Pinosylvin is an effective inhibitor of neutrophil activity, and is potentially useful as a complementary medicine in states associated with persistent inflammation. Pinosylvin has protection against oxidative stress through the induction of HO-1 in human RPE cells. Pinosylvin has inhibition against White-Rot and Brown-Rot Fungi.